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Article(4)
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Molecular Endocrinology(2)
Cell(1)
Proceedings of the National Academy of Sciences of the United States of America(1)
Identification of Ligands for DAF-12 that Govern Dauer Formation and Reproduction in C. elegans
ArticleAbstract: In response to environmental and dietary cues, the C. elegans orphan nuclear receptor, DAF-12, regulPalabras claves:Autores:Antebi A., Cummins C.L., Li T., Li Y., Mangelsdorf D.J., Motola D.L., Richard J. Auchus, Rottiers V., Sharma K.K., Suino-Powell K., Xu H.E.Fuentes:scopusIdentification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes
ArticleAbstract: Nematode parasitism is a worldwide health problem resulting in malnutrition and morbidity in over 1Palabras claves:Dafachronic acid, Parasitology, Pharmacology, X-ray crystal structureAutores:Conneely A., Gao X., Hawdon J.M., Kliewer S.A., Lok J., Mangelsdorf D.J., Motola D.L., Ogata C., Richard J. Auchus, Sharma K.K., Suino-Powell K., Wang Z., Xu H.E., Zhou X.Fuentes:scopusImpaired 17,20-lyase activity in male mice lacking cytochrome b<inf>5</inf> in leydig cells
ArticleAbstract: Androgen and estrogen biosynthesis in mammals requires the 17,20-lyase activity of cytochrome P450 1Palabras claves:Autores:Arlt W., Chomic R., Hughes B.A., Kliewer S.A., Liu J., Mangelsdorf D.J., Owen B.M., Richard J. Auchus, Sondhi V.Fuentes:scopusSynthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor
ArticleAbstract: The nuclear hormone receptor DAF-12 from Caenorhabditis elegans is activated by dafachronic acids, wPalabras claves:Autores:Cummins C.L., Mangelsdorf D.J., Motola D.L., Richard J. Auchus, Sharma K.K., Wang Z.Fuentes:scopus