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Pharmacogenomics Journal(3)
Journal of Psychiatric Research(1)
Translational Psychiatry(1)
Understanding Suicide: From Diagnosis to Personalized Treatment(1)
A combined high CYP2D6-CYP2C19 metabolic capacity is associated with the severity of suicide attempt as measured by objective circumstances
ArticleAbstract: This study examined, for the first time, whether a high CYP2D6-CYP2C19 metabolic capacity combinatioPalabras claves:Autores:Adrián LLerena, Blasco-Fontecilla H., Courtet P., Delgado A., Guillaume S., Jaussent I., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusABCB1 gene polymorphisms and violent suicide attempt among survivors
ArticleAbstract: Introduction: Those suicide attempters that choose violent methods dramatically diminish the possibiPalabras claves:ABCB1, Suicide attempt, Violent suicide methodsAutores:Adrián LLerena, Courtet P., Delgado A., Guillaume S., Jaussent I., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusHigh frequency of CYP2D6 ultrarapid metabolizers in Spain: Controversy about their misclassification in worldwide population studies
ArticleAbstract: A high frequency (7-10%) of CYP2D6 ultrarapid metabolizers estimated from the genotype (gUMs) has bePalabras claves:Autores:Adrián LLerena, Cobaleda J., de Andrés F., Delgado A., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusInterethnic variation of CYP2C19 alleles, 'pbkp_redicted' phenotypes and 'measured' metabolic phenotypes across world populations
ReviewAbstract: The present study evaluates the worldwide frequency distribution of CYP2C19 alleles and CYP2C19 metaPalabras claves:Autores:Adrián LLerena, Céspedes-Garro C., de Andrés F., Delgado A., Fricke-Galindo I., López-López M., Naranjo M.E.G., Penãs-Lledó E.M., Rodrigues-Soares F.Fuentes:scopusPharmacogenetic studies of suicide: Potential relevance of main polymorphic CYPs and ABCB1
Book PartAbstract: The present review focuses on existing information about studies of polymorphic genes mostly involvePalabras claves:Autores:Adrián LLerena, Delgado A., Penãs-Lledó E.M.Fuentes:scopusVEGF-related polymorphisms identified by GWAS and risk for major depression
ArticleAbstract: Depression is a common, severe, disabling mental disease that affects millions of people of all agesPalabras claves:Autores:Adrián LLerena, Cobaleda J., de Andrés F., Delgado A., Lamont J., Martin M., Murray H., Penãs-Lledó E.M., Siest G., Stathopoulou M.G., Visvikis-Siest S., Xie T.Fuentes:scopus