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Article(7)
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Journal of Biological Chemistry(4)
Biochemical and Biophysical Research Communications(1)
Cancer Research(1)
Journal of Immunology(1)
Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase
ArticleAbstract: Hypoxia-inducible factors (HIF) are heterodimeric (α/β) transcription factors that play a fundamentaPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Castellanos M.C., Feijóo-Cuaresma M., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Temes E.Fuentes:scopusEvidence for the Involvement of Diacylglycerol Kinase in the Activation of Hypoxia-inducible Transcription Factor 1 by Low Oxygen Tension
ArticleAbstract: Hypoxia-inducible factor 1 (HIF-1) induces a gene expression program essential for the cellular adapPalabras claves:Autores:Alfranca A., Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Mérida I., San Juan M.A., Vara A., Vidal F.Fuentes:scopusMacrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor
ArticleAbstract: Low oxygen tension areas are found in inflamed or diseased tissues where hypoxic cells induce survivPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Calzada M.J., Elorza A., Manuel Ortiz de Landázuri, Martín-Cofreces N.B., Martin-Puig S., Miro M., Olazabal I.M., Sánchez‐Madrid F.Fuentes:scopusRole of Iron (II)-2-Oxoglutarate-dependent Dioxygenases in the Generation of Hypoxia-induced Phosphatidic Acid through HIF-1/2 and von Hippel-Lindau-independent Mechanisms
ArticleAbstract: Hypoxia-inducible factors (HIF-1/HIF-2) govern the expression of critical genes for cellular adaptatPalabras claves:Autores:Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Temes E.Fuentes:scopusRole of diacylglycerol induced by hypoxia in the regulation of HIF-1α activity
ArticleAbstract: Hypoxia-inducible factor 1 (HIF-1) is a critical transcription factor for the adaptation to loweredPalabras claves:Diacylglycerol, HIF-1, Hypoxia, Lipid second messengers, Phosphatidic acid, Protein regulation, signal transductionAutores:Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Mérida I., Olmos G., Temes E.Fuentes:scopusSpecific Oncolytic Effect of a New Hypoxia-Inducible Factor-Dependent Replicative Adenovirus on von Hippel-Lindau-Defective Renal Cell Carcinomas
ArticleAbstract: Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are responsible for a hebkp_reditaryPalabras claves:Autores:Aragonés J., Castellanos M.C., Cuevas Y., Esteban M.A., Hernández-Alcoceba R., Manuel Ortiz de Landázuri, Martin-Puig S., Naranjo-Suárez S., Peso L.D.Fuentes:scopusThe von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen
ArticleAbstract: Most of the genes induced by hypoxia are regulated by a family of transcription factors termed hypoxPalabras claves:Autores:Castellanos M.C., Cuevas Y., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Peso L.D., Temes E.Fuentes:scopus