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Apoptosis: Modern Insights into Disease from Molecules to Man(1)
Bipolar Disorders(1)
Current Drug Metabolism(1)
Hippocampus(1)
International Journal of Developmental Neuroscience(1)
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scopus(9)
3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum
ArticleAbstract: 3-Nitropropionic acid (3-NP) is a neurotoxin that inhibits mitochondrial complex II and is used in aPalabras claves:3-nitropropionic acid, Calpain, CDK5, MEF2Autores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusCalpains as a target for therapy of neurodegenerative diseases: Putative role of lithium
ReviewAbstract: Lithium is a simple cation that has been used clinically since 1950 for the treatment of bipolar disPalabras claves:apoptosis, Calcium homeostasis, Calpain, Cell cycle control, Cytoskeleton, DNA damage, Kinases, Lithium, Neurodegeneration, neurodegenerative diseases, signal transduction, Tau kinasesAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Junyent F., Pallás M., Verdaguer E.Fuentes:scopusCell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
ArticleAbstract: This study was undertaken to investigate the potential role of cell cycle re-entry in an experimentaPalabras claves:apoptosis, cell cycle, Huntington's disease, StriatumAutores:Antoni Camins, Crespo-Biel N., Del Valle J., Duran-Vilaregut J., Ferrer I., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusEvidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro
ArticleAbstract: Lithium reduced striatal neurodegeneration induced in rats by 3-nitropropionic acid inhibiting calpaPalabras claves:3-nitropropionic acid, calcium, Calpain, Lithium, Neurodegenerative Disease, P35, SpectrinAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopusModulation of SIRT1 expression in different neurodegenerative models and human pathologies
ArticleAbstract: We examined the expression of SIRT1 in several experimental paradigms of human pathologies. We usedPalabras claves:3-nitropropionic acid, BRAIN, cell cycle, kainate, MPP+, rotenoneAutores:Alvira D., Antoni Camins, Canudas A.M., Crespo-Biel N., Ferrer I., Folch J., Gutiérrez-Cuesta J., Pallás M., Pizarro J.G., Sureda F.X., Tajes M., Yeste-Velasco M.Fuentes:scopusKainate induces AKT, ERK and cdk5/GSK3β pathway deregulation, phosphorylates tau protein in mouse hippocampus
ArticleAbstract: Acute treatment with kainate 30 mg/kg (KA) produced behavioral alterations and reactive gliosis. HowPalabras claves:Akt, Calpain, CDK5, GSK3β, Tau phosphorylationAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopusKainate-induced toxicity in the hippocampus: Potential role of lithium
ArticleAbstract: Objectives: We investigated the neuroprotective effects of lithium in an experimental neurodegeneratPalabras claves:calcium, Calpain, CDK5, Excitotoxicity, GSK-3, P35Autores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopusRegulation of GSK-3β by calpain in the 3-nitropropionic acid model
ArticleAbstract: Glycogen synthase kinase-3β (GSK-3β) is a crucial component in the cascade of events that culminatePalabras claves:Calpeptin, caspase, CDK5, SB-415286, SpectrinAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Gutiérrez-Cuesta J., Melchiorri D., Nicoletti F., Pallás M.Fuentes:scopusRole of calpain in apoptotic process involved in neurodegenerative diseases
Book PartAbstract: One of the main challenges facing researchers in neurosciences is to identify key molecules in neuroPalabras claves:Autores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopus