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Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
ArticleAbstract: We examined the expression of SIRT1 in several experimental paradigms of human pathologies. We usedPalabras claves:3-nitropropionic acid, BRAIN, cell cycle, kainate, MPP+, rotenoneAutores:Alvira D., Antoni Camins, Canudas A.M., Crespo-Biel N., Ferrer I., Folch J., Gutiérrez-Cuesta J., Pallás M., Pizarro J.G., Sureda F.X., Tajes M., Yeste-Velasco M.Fuentes:scopusKainate induces AKT, ERK and cdk5/GSK3β pathway deregulation, phosphorylates tau protein in mouse hippocampus
ArticleAbstract: Acute treatment with kainate 30 mg/kg (KA) produced behavioral alterations and reactive gliosis. HowPalabras claves:Akt, Calpain, CDK5, GSK3β, Tau phosphorylationAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopus