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Calpains as a target for therapy of neurodegenerative diseases: Putative role of lithium
ReviewAbstract: Lithium is a simple cation that has been used clinically since 1950 for the treatment of bipolar disPalabras claves:apoptosis, Calcium homeostasis, Calpain, Cell cycle control, Cytoskeleton, DNA damage, Kinases, Lithium, Neurodegeneration, neurodegenerative diseases, signal transduction, Tau kinasesAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Junyent F., Pallás M., Verdaguer E.Fuentes:scopusEvidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro
ArticleAbstract: Lithium reduced striatal neurodegeneration induced in rats by 3-nitropropionic acid inhibiting calpaPalabras claves:3-nitropropionic acid, calcium, Calpain, Lithium, Neurodegenerative Disease, P35, SpectrinAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M.Fuentes:scopus