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Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats
ArticleAbstract: Purpose: Neuroinflammation may contribute to the pathogenesis of the cognitive symptoms of postoperaPalabras claves:aging, COGNITION, dopamine, Haloperidol, neuroinflammationAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusAcute postoperative pain exacerbates neuroinflammation and related delirium-like cognitive dysfunction in rats
ArticleAbstract: The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative deliPalabras claves:Delirium, neuroinflammation, postoperative painAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Koyama T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusEffects and underlying mechanisms of endotoxemia on post-incisional pain in rats
ArticleAbstract: Aims The aim of the present study was to investigate the effects and underlying mechanisms of endotoPalabras claves:Analgesics, Endotoxin, postoperative painAutores:Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusInvolvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats
ArticleAbstract: Purpose: The purpose of this study was to investigate the age-, time-, and brain region-dependent poPalabras claves:Attention, Cognitive dysfunction, Fear memory, neuroinflammation, Postoperative deliriumAutores:Aoyama B., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusResveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats
ArticleAbstract: The maladaptive response of aged microglia to surgery and consequent neuroinflammation plays a key pPalabras claves:Microglia, neuroinflammation, postoperative cognitive dysfunction, ResveratrolAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusRole of neurosteroid allopregnanolone on age-related differences in exercise-induced hypoalgesia in rats
ArticleAbstract: The beneficial effects of physical activity for pain are denominated exercise-induced hypoalgesia (EPalabras claves:acute pain, aging, Allopregnanolone, Exercise, NeurosteroidAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusPregabalin can prevent, but not treat, cognitive dysfunction following abdominal surgery in aged rats
ArticleAbstract: Aims The present study aimed to explore the preventive or therapeutic effect of peri-operative pregaPalabras claves:Microglia, neuroinflammation, Post-operative cognitive dysfunctionAutores:Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusThe role of hippocampal insulin signaling on postoperative cognitive dysfunction in an aged rat model of abdominal surgery
ArticleAbstract: Aims This study aimed to investigate the role of central insulin signaling, including glycogen synthPalabras claves:Insulin, Microglia, neuroinflammation, Postoperative cognitive disordersAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopus