Mostrando 4 resultados de: 4
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Publisher
Cell Chemical Biology(1)
Clinical Cancer Research(1)
Proceedings of the National Academy of Sciences of the United States of America(1)
Steroids(1)
Área de conocimiento
Cáncer(3)
Origen
scopus(4)
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
ArticleAbstract: In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapPalabras claves:5-alpha-androstanedione, Abiraterone acetate, Hormonal therapy, Hormone resistance, Tumor metabolismAutores:Chang K.H., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N., Watumull L., Zhao Y.Fuentes:scopusMolecular pathways: Inhibiting steroid biosynthesis in prostate cancer
ReviewAbstract: A significant proportion of castration-resistant prostate cancers (CRPC) remains driven by ligand acPalabras claves:Autores:Attard G., Ferraldeschi R., Richard J. Auchus, Sharifi N.Fuentes:scopusSteroid biosynthesis and prostate cancer
ReviewAbstract: The pathways of androgen biosynthesis in human beings have been studied for decades, and the major pPalabras claves:Abiraterone acetate, androgen receptor, Dihydrotestosterone, Prostate cancer, steroidogenesis, TestosteroneAutores:Richard J. Auchus, Sharifi N.Fuentes:scopusSteroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities
ArticleAbstract: Galeterone is a steroidal CYP17A1 inhibitor, androgen receptor (AR) antagonist, and AR degrader, undPalabras claves:3βHSD, abiraterone, Androgens, CYP17A1, galeterone, metabolism, Prostate cancer, steroidsAutores:Alyamani M., Berk M.P., Li J., Li Z., Richard J. Auchus, Sharifi N., Tang J., Upadhyay S.K.Fuentes:scopus