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Article(10)
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Toxicon(3)
Journal of Receptors and Signal Transduction(2)
American Journal of Respiratory Cell and Molecular Biology(1)
Archivos Venezolanos de Farmacologia y Terapeutica(1)
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology(1)
Characterization of a G protein-coupled guanylyl cyclase-B receptor from bovine tracheal smooth muscle
ArticleAbstract: A G protein-coupled natriuretic peptide-guanylyl cyclase receptor-B (NPR-B) located in plasma membraPalabras claves:cGMP, G proteins, Mastoparan, Natriuretic peptides, NPR-BAutores:Adolfo Borges, Alfonzo M.J., De Aguilar E., De Alfonzo R.G., De Bécemberg I.L., De Murillo A., De Villarroel S.S.Fuentes:scopusCoupling of M3 acetylcholine receptor to Gq16 activates a natriuretic peptide receptor guanylyl cyclase
ArticleAbstract: Muscarinic activation of tracheal smooth muscle (TSM) involves a M3AChR/heterotrimeric-G protein/NPRPalabras claves:G proteins, Guanylyl cyclases, Muscarinic receptors, NPR-B, Tracheal smooth muscleAutores:Adolfo Borges, Alfonzo M.J., Bruges G., De Alfonzo R.G., De Bécemberg I.L., De Toba G.F., De Villarroel S.S., Pláceres F.Fuentes:scopusDiversity of long-chain toxins in Tityus zulianus and Tityus discrepans venoms (Scorpiones, Buthidae): Molecular, immunological, and mass spectral analyses
ArticleAbstract: In Venezuela, stings by Tityus zulianus scorpions produce cardiorespiratory arrest, whereas envenomiPalabras claves:3′-UTR, antivenom, Mass spectrometry, scorpion toxin, scorpion venom, Tityus discrepans, Tityus zulianus, Toxin diversity, VENEZUELAAutores:Adolfo Borges, Alfonzo M.J., García C.C., Jowers M.J., Lugo E., Op den Camp H.J.M.Fuentes:scopusMolecular systematics of the neotropical scorpion genus Tityus (Buthidae): The historical biogeography and venom antigenic diversity of toxic Venezuelan species
ArticleAbstract: We provide a mitochondrial DNA-based phylogenetic hypothesis for 21 Tityus species collected in VenePalabras claves:Autores:Adolfo Borges, Alfonzo M.J., Bermingham E., Herrera N., Sanjur O.I.Fuentes:scopusPancreatic toxicity in mice elicited by Tityus zulianus and Tityus discrepans scorpion venoms
ArticleAbstract: Envenoming by Tityus discrepans (TD) scorpions in northcentral Venezuela mainly causes pancreatic anPalabras claves:Amylase, PANCREATITIS, scorpion venom, TityusAutores:Adolfo Borges, Alfonzo M.J., Céspedes G., Hernández A., Trejo E., Vargas A.M.Fuentes:scopusIn vitro leishmanicidal activity of Tityus discrepans scorpion venom
ArticleAbstract: Leishmania parasites are sensitive to peptides with antimicrobial and ion-channel inhibitory activitPalabras claves:Autores:Adolfo Borges, Alfonzo M.J., Alvarez M., De Sousa L., Delgado O., Jorquera A., Op den Camp H.J.M., Silva S., Velasco E.Fuentes:scopusMolecular and biochemical characterization of a CNP-sensitive guanylyl cyclase in bovine tracheal smooth muscle
ArticleAbstract: Muscarinic activation of bovine tracheal smooth muscle (BTSM) is involved in cyclic guanosine monophPalabras claves:Autores:Adolfo Borges, Alfonzo M.J., González de Alfonzo R., Lippo de Béemberg I., Sánchez de Villarroel S., Winand N.J.Fuentes:scopusIsolation, molecular cloning and functional characterization of a novel β-toxin from the Venezuelan scorpion, Tityus zulianus
ArticleAbstract: Sting in children by Tityus zulianus scorpions (western Venezuela) often produces cardiorespiratoryPalabras claves:Beta-scorpion toxin, ESI/MS, electrospray ionization mass spectrometry, K , voltage-gated potassium channel V, Na , voltage-gated sodium channel V, Receptor site-4, Sodium channel activation, Tityus, Tityus zulianusAutores:Adolfo Borges, Alfonzo M.J., García C.C., Heinemann S.H., Leipold E., Winand N.J.Fuentes:scopusTityus zulianus and Tityus discrepans venoms induced massive autonomic stimulation in mice
ArticleAbstract: Venezuelan scorpion envenomation is a public health problem produced by Tityus discrepans (TD) and TPalabras claves:Cathecholamine release, Nor-epinephrine, Scorpion venoms, Tityus discrepans, Tityus zulianusAutores:Adolfo Borges, Alfonzo M.J., González de Alfonzo R., Lippo de Becemberg I., Trejo E.Fuentes:scopusTityus zulianus venom induces massive catecholamine release from PC12 cells and in a mouse envenomation model
ArticleAbstract: Scorpion envenomation is a public health problem in Venezuela, mainly produced by Tityus discrepansPalabras claves:Catecholamine release, Dopamine release, Epinephrine, PC12 cells, Scorpion venoms, Tityus discrepans, Tityus zulianusAutores:Adolfo Borges, Alfonzo M.J., González de Alfonzo R., Lippo de Becemberg I., Nañez B., Trejo E.Fuentes:scopus