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BioMed Research International(3)
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Biochemical and functional characterization of parawixia bistriata spider venom with potential proteolytic and larvicidal activities
ArticleAbstract: Toxins purified from the venom of spiders have high potential to be studied pharmacologically and biPalabras claves:Autores:Coutinho-Neto A., De Almeida E Silva A., de Azevedo Calderon L., Fernandes C.F.C., Gimenez G.S., Kayano A.M., Marcussi S., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Trindade F., Zuliani J.P.Fuentes:scopusBiodiversity as a source of bioactive compounds against snakebites
ArticleAbstract: Snakebites are a frequently neglected public health issue in tropical and subtropical countries. AccPalabras claves:Anti-snake venom, Anti-snake venom compounds, Ophidian venom, Serum, Serum therapy, snakebiteAutores:Carvalho B.M.A., Costa T.R., de Azevedo Calderon L., Fernandes C.F.C., Fernandes R.S., Guimarães C.L.S., Hage-Melim L.I.S., Marcussi S., Moreira-Dill L.S., Saulo L. Silva, Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusAnti-snake venom activities of extracts and fractions from callus cultures of Sapindus saponaria
ArticleAbstract: Context: Sapindus saponaria L. (Sapindaceae) bark, root, and fruits are used as sedatives and to trePalabras claves:Anti-snake venom, Anti-toxins, Medicinal Plants, Natural inhibitors, Snake venomsAutores:Da Silva M.L., Fernandes R.S., França S.C., Janurio A.H., Lourenço M.V., Marcussi S., Pereira P.S., Saulo L. Silva, Soares A.M.Fuentes:scopusAntitumoral activity of snake venom proteins: New trends in cancer therapy
ReviewAbstract: For more than half a century, cytotoxic agents have been investigated as a possible treatment for caPalabras claves:Autores:Carvalho B.M.A., de Azevedo Calderon L., De Moura A.A., Fernandes C.F.C., Grabner A.N., Marcussi S., Mazzi M.V., Nomizo A., Saulo L. Silva, Soares A.M., Sobrinho J.C., Stábeli R.G., Zaqueo K.D., Zuliani J.P.Fuentes:scopusGallic acid anti-myotoxic activity and mechanism of action, a snake venom phospholipase A<inf>2</inf> toxin inhibitor, isolated from the medicinal plant Anacardium humile
ArticleAbstract: Snakebite envenoming is the cause of an ongoing health crisis in several regions of the world, partiPalabras claves:Gallic acid, Phospholipase A inhibitor 2, Snake venomsAutores:Cardoso F.F., Costa T.R., Fernandes C.A.H., Fontes M.R.M., Francisco A.F., Gomes A.A.S., Guimarães C.L.S., Marcussi S., Moreira-Dill L.S., Oliveira H.C., Pereira P.S., Saulo L. Silva, Soares A.M., Zuliani J.P.Fuentes:scopusGenotoxic effect of Bothrops snake venoms and isolated toxins on human lymphocyte DNA
ArticleAbstract: In the present study, micronucleus with cytokinesis blocking and comet assays were used to evaluatePalabras claves:Bothrops snake, Comet, Genotoxic potential, Micronucleus, Snake venom toxinsAutores:de Azevedo Calderon L., Greggi Antunes L.M., Marcussi S., Menaldo D.L., Santos-Filho N.A., Saulo L. Silva, Silva Pereira L.L., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusEnzymatic and structural characterization of a basic phospholipase A <inf>2</inf> from the sea anemone Condylactis gigantea
ArticleAbstract: This work aimed at the isolation and structural/functional characterization of a phospholipase A 2 (Palabras claves:Condylactis gigantea, Functional characterization, molecular modeling, Phospholipase A 2, Phylogenetic analysis, Primary structure, Sea anemonesAutores:Fuly A.L., González J., Marchi-Salvador D.P., Marcussi S., Monte A.d., Romero L., Saulo L. Silva, Silva F.P., Soares A.M., Stábeli R.G.Fuentes:scopusEvaluation of the genotoxicity of Crotalus durissus terrificus snake venom and its isolated toxins on human lymphocytes
ArticleAbstract: In the present study, experiments were carried out to evaluate the mutagenic potential and genotoxicPalabras claves:Comet, Crotalus durissus terrificus, genotoxicity, Micronucleus, Snake venom toxinsAutores:Greggi Antunes L.M., Marcussi S., Mazzi M.V., Menaldo D.L., Santos P.R.S., Santos-Filho N.A., Saulo L. Silva, Silveira L.B., Soares A.M., Stábeli R.G.Fuentes:scopusEvaluation of the hypoglycemic properties of Anacardium humile aqueous extract
ArticleAbstract: The antihyperglycemic effects of several plant extracts and herbal formulations which are used as anPalabras claves:Autores:Couto L.B., de Azevedo Calderon L., França S.C., Guimarães C.L.S., Marcussi S., Pereira A.M.S., Pereira P.S., Saulo L. Silva, Silva Pereira L.L., Soares A.M., Stábeli R.G., Urzêda M.A.Fuentes:scopusIsolation and expression of a hypotensive and anti-platelet acidic phospholipase A<inf>2</inf> from Bothrops moojeni snake venom
ArticleAbstract: Phospholipases A2 are important components of snake venoms, the basic isoforms have been more extensPalabras claves:Acidic phospholipase A 2, Anti-platelet, Bothrops moojeni, Hypotension, Snake venomAutores:Arantes E.C., Fuly A.L., Marchi-Salvador D.P., Marcussi S., Nomizo A., Santos-Filho N.A., Saulo L. Silva, Silva F.P., Silveira L.B., Soares A.M., Stábeli R.G.Fuentes:scopus