Mostrando 10 resultados de: 35
Filtros aplicados
Publisher
Journal of Alzheimer's Disease(3)
Apoptosis(2)
Current Neuropharmacology(2)
Expert Opinion on Drug Discovery(2)
Expert Opinion on Investigational Drugs(2)
Área temáticas
Enfermedades(26)
Fisiología humana(8)
Bioquímica(5)
Ginecología, obstetricia, pediatría, geriatría(5)
Medicina y salud(4)
Origen
scopus(35)
Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons
ArticleAbstract: The mechanism involved in neuronal apoptosis is largely unknown. Studies performed on neuronal cellPalabras claves:Cerebellar granule cells, MPP+, Resveratrol, Serum and potassium withdrawal, Sirt1, sirtinolAutores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Yeste-Velasco M.Fuentes:scopusBenzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
ArticleAbstract: Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to theirPalabras claves:Alzheimer's disease, benzodiazepines, COGNITION, dementia, RISK FACTORSAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusAn overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusAnti-inflammatory role of Leptin in glial cells through p38 MAPK pathway inhibition
ArticleAbstract: Background In the present work, we studied the modulatory effect of Leptin (Lep) against pro-inflammPalabras claves:Caspase-3, Cytochrome-c, Glial cells, iNOS, leptin, p38 MAPKAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Martí A., Martínez N., Miguel Marin, Patraca I., Pedros I., Sureda F.X., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusA molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286
ArticleAbstract: Pharmacological GSK-3 inhibitors are potential drugs for the treatment of neurodegenerative diseasesPalabras claves:apoptosis, B65 cells, Cdc2, GSK3, Lithium, SB-415286Autores:Antoni Camins, Esparza J.L., Folch J., Jordan J., Pallás M., Pizarro J.G.Fuentes:scopusA novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
ArticleAbstract: Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the globaPalabras claves:Alzheimer’s disease, BACE1, BDNF, cognitive decline, dendritic spines, high-fat diet, neuroinflammation, Rhein-huprine hybrid, Tau, TLR4Autores:Antoni Camins, Auladell C., Bulló M., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Muñoz-Torrero D., Olloquequi J., Parcerisas A., Pont C., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusCyclin-Dependent Kinases
Book PartAbstract: Cyclin-dependent kinases (CDKs) are a family of serine/threonine protein kinases whose activity depePalabras claves:CDK protein family, CDK-activating kinase, CDK1, CDK5, CDKs involved in transcription, Cip/Kip family, INK4 family, Pho85Autores:Antoni Camins, Folch J., Pizarro J.G.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopus