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A metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusA molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286
ArticleAbstract: Pharmacological GSK-3 inhibitors are potential drugs for the treatment of neurodegenerative diseasesPalabras claves:apoptosis, B65 cells, Cdc2, GSK3, Lithium, SB-415286Autores:Antoni Camins, Esparza J.L., Folch J., Jordan J., Pallás M., Pizarro J.G.Fuentes:scopusA novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
ArticleAbstract: Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the globaPalabras claves:Alzheimer’s disease, BACE1, BDNF, cognitive decline, dendritic spines, high-fat diet, neuroinflammation, Rhein-huprine hybrid, Tau, TLR4Autores:Antoni Camins, Auladell C., Bulló M., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Muñoz-Torrero D., Olloquequi J., Parcerisas A., Pont C., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusComparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons
ArticleAbstract: The mechanism involved in neuronal apoptosis is largely unknown. Studies performed on neuronal cellPalabras claves:Cerebellar granule cells, MPP+, Resveratrol, Serum and potassium withdrawal, Sirt1, sirtinolAutores:Alvira D., Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Yeste-Velasco M.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusCorrection to: Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease (Molecular Neurobiology, (2018), 55, 9, (7327-7339), 10.1007/s12035-018-0868-4)
OtherAbstract: The original version of this article unfortunately contained mistake. The authors found that Fig. 4.Palabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carrera M.V., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusAdipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer’s disease
ArticleAbstract: A growing body of evidence suggests that β-amyloid peptides (Aβ) are unlikely to be the only factorPalabras claves:ALZHÉIMER, APP/PS1, hippocampus, leptin, prolactinAutores:Abad S., Antoni Camins, Artiach G., Folch J., Pallás M., Pedros I., Petrov D., Ramon-Duaso C., Sureda F.X., Zárate C.B.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopus