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Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
ArticleAbstract: In this study, the effects of melatonin on MPP+-treated cerebellar granule neurons (CGNs) in culturePalabras claves:apoptosis, Calpain, caspase, CDK5, Cerebellar granule cells, MPP +Autores:Acuña-Castroviejo D., Alvira D., Antoni Camins, Folch J., Pallás M., Tajes M., Verdaguer E.Fuentes:scopusInvolvement of calpain activation in neurodegenerative processes
ReviewAbstract: One of the challenges in the coming years will be to better understand the mechanisms of neuronal cePalabras claves:amyloid, Calpain, caspase, Excitotoxicity, glutamate, Mitochondria, neurodegenerative diseasesAutores:Antoni Camins, Folch J., Pallás M., Verdaguer E.Fuentes:scopusThe role of CDK5/P25 formation/inhibition in neurodegeneration
ReviewAbstract: Cdk5 is an atypical cyclin-dependent kinase localized in the brain, and its activity is dependent upPalabras claves:Autores:Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E.Fuentes:scopus