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A comprehensive review of autoantibodies in primary Sjögren's syndrome: Clinical phenotypes and regulatory mechanisms
ReviewAbstract: Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial lymphocyticPalabras claves:Anti-La/SSB, Anti-Ro/SSA, Autoantibodies, Salivary gland epithelial cells, Sjörgen's syndromeAutores:Kapsogeorgou E.K., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopusRNA recognition motif (RRM) of La/SSB: The bridge for interparticle spreading of autoimmune response to U1-RNP
ArticleAbstract: Systemic lupus erythematosus (SLE) is characterized by the production of grouped sets of autoantibodPalabras claves:Autores:Latreille M., Nikolaos C. Kyriakidis, Routsias J.G., Tzioufas A.G.Fuentes:googlescopusStudy of microRNAs (miRNAs) that are pbkp_redicted to target the autoantigens Ro/SSA and La/SSB in primary Sjögren's Syndrome
ArticleAbstract: The elevated tissue expression of Ro/SSA and La/SSB autoantigens appears to be crucial for the generPalabras claves:Autoantigens, La/SSB, miRNAs, Ro52/TRIM21, Ro60/TROVE2, Sjögren's syndromeAutores:Gourzi V.C., Kapsogeorgou E.K., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopusToll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear bkp_redistribution in salivary gland epithelial cells, partially via type I interferon pathway
ArticleAbstract: Up-regulated expression of Ro52/tripartite motif-containing protein 21 (TRIM21), Ro60/TROVE domain fPalabras claves:Ro52/TRIM21 autoantigen, Salivary gland epithelial cells, Sjögren's syndrome, TLR-3, Type I interferonsAutores:Baltatzis G.E., Gourzi V.C., Kapsogeorgou E.K., Konsta O.D., Nikolaos C. Kyriakidis, Tzioufas A.G.Fuentes:googlescopus