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Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep
ArticleAbstract: Background: Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of brain injurPalabras claves:hypoxic-ischemic encephalopathy, inflammation, Microglia, neutrophils, Oligodendrocytes, Preterm, spleenAutores:Andriessen P., Antonio Wenceslao Danilo Gavilanes, Cleutjens J.P.M., Collins J.J.P., De Munter S., Germeraad W.T.V., Jellema R.K., Jennekens W., Kramer B.W., Kuypers E., Lima Passos V., Ophelders D.R.M.G., Seehase M., Steinbusch H.W.M., Vanderlocht J., Vles H.J.S., Wolfs T.G.A.M., Zwanenburg A.Fuentes:scopusIncreased EEG delta frequency corresponds to chorioamnionitis-related brain injury
ArticleAbstract: We evaluated the impact of chorioamnionitis on the intrapartal EEG delta frequency in the non-anesthPalabras claves:CFAM, chorioamnionitis, CNS, EEG, EXIT procedure, fetal inflammation, LPS, Neurological developmentAutores:Antonio Wenceslao Danilo Gavilanes, Gantert M., Kramer B.W., Seeldrayers S., Strackx E., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopusIncreased number of cerebellar granule cells and astrocytes in the internal granule layer in sheep following prenatal intra-amniotic injection of lipopolysaccharide
ArticleAbstract: Chorioamnionitis is an important problem in perinatology today, leading to brain injury and neurologPalabras claves:astrocytes, Cerebellum, chorioamnionitis, FETAL, Granule cell loss, Intra-amniotic, LPS, stereologyAutores:Antonio Wenceslao Danilo Gavilanes, Gantert M., Garnier Y., Hürter H., Kramer B.W., Lemmens M.A.M., Moers V., Rieke R., Steinbusch H.W.M., Strackx E., Van Kooten I.A.J., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopusMaturational changes in automated EEG spectral power analysis in preterm infants
ArticleAbstract: Our study aimed at automated power spectral analysis of the EEG in preterm infants to identify changPalabras claves:Autores:Andriessen P., Antonio Wenceslao Danilo Gavilanes, Jennekens W., Katgert T., Kramer B.W., Niemarkt H.J., Oetomo S.B., Pasman J., Van Pul C., Zimmermann L.J.I.Fuentes:scopusIntra-Amniotic LPS Induced Region-Specific Changes in Presynaptic Bouton Densities in the Ovine Fetal Brain
ArticleAbstract: Rationale. Chorioamnionitis has been associated with increased risk for fetal brain damage. AlthoughPalabras claves:Autores:Antonio Wenceslao Danilo Gavilanes, Gussenhoven R., Jellema R.K., Kramer B.W., Rieke R., Strackx E., Vles J.S.H.Fuentes:scopusPerinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis
ArticleAbstract: Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the saPalabras claves:Developmental disorders, Epidemiological, Huntington's disease, Modifier, neonatalAutores:Anderson D.G., Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Rodrigues F.B., Wild E.J., Winkens B.Fuentes:scopusPreterm perinatal hypoxia-ischemia does not affect somatosensory evoked potentials in adult rats
ArticleAbstract: Somatosensory evoked potentials (SSEPs) are a valuable tool to assess functional integrity of the soPalabras claves:Cerebral palsy, Hypoxia-ischemia, Preterm brain, Rat model, Somatosensory evoked potentialAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Bergs P., Kramer B.W., Peter A. Chedraui, van Kranen-Mastenbroek V.H.J.M., van Mechelen R., Vermeer M., Vles J.S.H.Fuentes:scopusPreconditioning by oxygen-glucose deprivation preserves cell proliferation and reduces cytotoxicity in primary astrocyte cultures
ArticleAbstract: Hypoxic-ischemic preconditioning (HIPC) has a neuroprotective effect against a subsequent, more sevePalabras claves:astrocytes, cytokines, Hypoxia-ischemia, Hypoxic-ischemic preconditioning, Oxygen-glucose deprivation, ProliferationAutores:Antonio Wenceslao Danilo Gavilanes, Kramer B.W., Nikiforou M., Strackx E., Vlassaks E., Vles J.S.H.Fuentes:scopusSystemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy
ArticleAbstract: There is an urgent need for therapies that could reduce the disease burden of preterm hypoxic-ischemPalabras claves:hypoxic-ischemic encephalopathy, Neurodevelopment, Preterm brain, Stem cell therapyAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Mays R.W., Paes D., Peter A. Chedraui, Robertson N.J., Steinbusch H.W.M., Vaes B., van den Hove D.L.A., van Mechelen R., Vermeer M.Fuentes:scopusThe effects of fetal and perinatal asphyxia on neuronal cytokine levels and ceramide metabolism in adulthood
ArticleAbstract: In a rat model of global fetal and perinatal asphyxia, we investigated if asphyxia and long-lastingPalabras claves:Ceramides, neuroinflammation, Perinatal asphyxia, preconditioningAutores:Antonio Wenceslao Danilo Gavilanes, Deville S., Kramer B.W., Martinez-Martinez P., Strackx E., Vlassaks E., Vles J.S.H.Fuentes:scopus