The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21

Article

Abstract: Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxyla

Palabras claves:

17α-Hydroxylase/17,20-lyase, 21-hydroxylase, CYP17, CYP21, Cytochrome P450c17, Cytochrome P450c21, ent-Progesterone, Enzyme inhibition, molecular dynamics, Type I difference spectrum

Autores:

Boswell C., Bruce K., Covey D.F., Gupta M.K., Kumar A., Rath N., Richard J. Auchus

Fuentes:

scopus