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Nimotuzumab induces NK cell activation, cytotoxicity, dendritic cell maturation and expansion of EGFR-specific T cells in head and neck cancer patients
ArticleAbstract: Survival benefit and long-term duration of clinical response have been seen using the epidermal growPalabras claves:head and neck cancer, Human epidermal growth factor receptor, monoclonal antibodies, Natural killer cells, T cellsAutores:Barroso M.C., Concha-Benavente F., Cuevas I., Ferris R.L., Frómeta C., García-Bates T.M., González A., Gonzalez Z., Hechavarría E., Lavastida A., Lugiollo M., Mazorra Z., Mestre B.F., Srivastava R.M., Tania Crombet, Valdés A.Fuentes:scopusNimotuzumab: beyond the EGFR signaling cascade inhibition
ReviewAbstract: One of the most known oncogenes is the epidermal growth factor receptor (EGFR) family. It activatesPalabras claves:antibody-dependent cell mediated cytotoxicity (ADCC), eGFR, HLA class I molecules, monoclonal antibodies, Natural killer cells, T cellsAutores:Chao L., Iznaga N., Lavastida A., Mazorra Z., Ramos M., Sanchez B., Tania CrombetFuentes:scopus