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Expression and purification of soluble recombinant SapM from Mycobacterium tuberculosis
ArticleAbstract: SapM from Mycobacterium tuberculosis is a secreted phosphatase critical for pathogen survival insidePalabras claves:Active enzyme, Protein expression, Protein purification, SapM, Sarkosyl, Soluble protein, TuberculosisAutores:Cavet J.S., Paulina Fernandez-Soto, Tabernero L.Fuentes:googlescopusDiscovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis
ArticleAbstract: SapM is a secreted virulence factor from Mycobacterium tuberculosis critical for pathogen survival aPalabras claves:Autores:Casulli J., Cavet J.S., Jowitt T.A., Paulina Fernandez-Soto, Rodríguez-Fernández P., Solano-Castro D., Tabernero L., Travis M.A.Fuentes:googlescopusInfant Alveolar Macrophages Are Unable to Effectively Contain Mycobacterium tuberculosis
ArticleAbstract: Infants are more likely to develop lethal disseminated forms of tuberculosis compared with older chiPalabras claves:Chemokine, Infant, Lung, Lysosome, macrophage, transcriptomics, TuberculosisAutores:Arkwright P.D., Cavet J.S., Connolly E., Goenka A., Grainger J.R., Hussell T., Morgan D., Nichani J., Paulina Fernandez-Soto, Prise I.E.Fuentes:googlescopusMechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
ArticleAbstract: Mycobacterium tuberculosis (Mtb) SapM is a secreted virulence factor critical for intracellular survPalabras claves:Autores:Bruce A.J.E., Cavet J.S., Fielding A.J., Paulina Fernandez-Soto, Tabernero L.Fuentes:googlescopus