Mostrando 10 resultados de: 11
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Journal of Clinical Endocrinology and Metabolism(5)
Proceedings of the National Academy of Sciences of the United States of America(2)
Endocrine Reviews(1)
Endocrinology(1)
Journal of Biological Chemistry(1)
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Enfermedades(6)
Farmacología y terapéutica(5)
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Ginecología, obstetricia, pediatría, geriatría(2)
Medicina y salud(2)
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scopus(11)
Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer
ArticleAbstract: Context: Abiraterone acetate is a small-molecule cytochrome P450 17A1 (CYP17A1) inhibitor that is acPalabras claves:Autores:Arlt W., Attard G., Cassidy A.M., De Bono J.S., Dowsett M., Folkerd E., Hughes B.A., Oommen N.B., Reid A.H.M., Richard J. Auchus, Thompson E.Fuentes:scopusCongenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management
ReviewAbstract: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting cortisolPalabras claves:21-hydroxylase deficiency, aldosterone, cortisol, CYP21A2, Glucocorticoid, mineralocorticoid, Steroid biosynthesisAutores:Arlt W., Faisal Ahmed S., Falhammar H., Flück C.E., Guasti L., Huebner A., Kortmann B.B.M., Krone N., Merke D.P., Miller W.L., Nordenström A., Reisch N., Richard J. Auchus, Sandberg D.E., Speiser P.W., Stikkelbroeck N.M.M.L., Touraine P., Utari A., van der Grinten H.L.C., White P.C., Wudy S.A.Fuentes:scopusCongenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: An endocrine society* clinical practice guideline
ArticleAbstract: Objective: To update the congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency cliPalabras claves:Autores:Arlt W., Baskin L.S., Conway G.S., Merke D.P., Meyer-Bahlburg H.F.L., Miller W.L., Murad M.H., Oberfield S.E., Richard J. Auchus, Speiser P.W., White P.C.Fuentes:scopusApproach to the patient: The adult with congenital adrenal hyperplasia
ReviewAbstract: The most common form of congenital adrenal hyperplasia is steroid 21-hydroxylase deficiency (21OHD).Palabras claves:Autores:Arlt W., Richard J. AuchusFuentes:scopusAlternative androgen pathway biosynthesis drives fetal female virilization in P450 oxidoreductase deficiency
OtherAbstract:Palabras claves:Autores:Arlt W., Hanley N.A., Reisch N., Richard J. Auchus, Shackleton C.H.L.Fuentes:scopusAlternative pathway androgen biosynthesis and human fetal female virilization
ArticleAbstract: Androgen biosynthesis in the human fetus proceeds through the adrenal sex steroid precursor dehydroePalabras claves:5α-dihydrotestosterone, Alternative androgen pathway, Congenital adrenal hyperplasia, Fetal androgen biosynthesis, Human sexual differentiationAutores:Arlt W., Asby D.J., Berry A., Dhir V., Hanley N.A., Krone N., Nogueira E.F., Reisch N., Richard J. Auchus, Shackleton C.H.L., Taylor A.E.Fuentes:scopusEnzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome
ArticleAbstract: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting approximately 5-10% of womPalabras claves:Autores:Arlt W., Dunaif A., Geller D.H., Martens J.W.M., Miller W.L., Ossovskaya V.S., Richard J. Auchus, Rodriguez H.Fuentes:scopusErratum: Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: An endocrine society clinical practice guideline (The Journal of Clinical Endocrinology and Metabolism (2018) 103:11 (4043-4088) DOI: 10.1210/jc.2018-01865)
OtherAbstract: The above-mentioned guideline by Speiser PW, Azziz R, Baskin LS, Ghizzoni L, Hensle TW, Merke DP, MePalabras claves:Autores:Arlt W., Baskin L.S., Conway G.S., Merke D.P., Meyer-Bahlburg H.F.L., Miller W.L., Murad M.H., Oberfield S.E., Richard J. Auchus, Speiser P.W., White P.C.Fuentes:scopusMolecular evolution of adrenarche: Structural and functional analysis of P450c17 from four rimate species
ArticleAbstract: Adrenarche is the prepubertal onset of increased adrenal secretion of 19-carbon steroids, especiallyPalabras claves:Autores:Arlt W., Martens J.W.M., Miller W.L., Richard J. Auchus, Song M., Wang J.Fuentes:scopusImpaired 17,20-lyase activity in male mice lacking cytochrome b<inf>5</inf> in leydig cells
ArticleAbstract: Androgen and estrogen biosynthesis in mammals requires the 17,20-lyase activity of cytochrome P450 1Palabras claves:Autores:Arlt W., Chomic R., Hughes B.A., Kliewer S.A., Liu J., Mangelsdorf D.J., Owen B.M., Richard J. Auchus, Sondhi V.Fuentes:scopus