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Current Computer-Aided Drug Design(1)
International Journal of Molecular Sciences(1)
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QSAR and Combinatorial Science(1)
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Farmacología(3)
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scopus(4)
Anticonvulsant activity of ringed enaminones: A QSAR study
ArticleAbstract: The formalism of the QSAR Theory is employed to establish mathematical relationships that link the mPalabras claves:ab initio calculations, ED 50, Enaminones, Epilepsy, Linear free energy relationships, Molecular descriptors, QSAR TheoryAutores:Castro E.A., Estrada M.R., Martinez J.C.G., Pablo R. Duchowicz, Zamarbide G.N.Fuentes:scopusA multivariate QSAR study on the anticonvulsant activity of acetamido-N-benzylacetamide derivatives. Influence of different molecular descriptors
ArticleAbstract: A quantitative structure activity relationship analysis was applied to a library of 51 benzylacetamiPalabras claves:Autores:Castro E.A., Estrada M.R., Martinez J.C.G., Pablo R. DuchowiczFuentes:scopusLacosamide derivatives with anticonvulsant activity as carbonic anhydrase inhibitors. Molecular modeling, docking and QSAR analysis
ArticleAbstract: Lacosamide is an anticonvulsant drug which presents carbonic anhydrase inhibition. In this paper, wePalabras claves:Anticonvulsant activity, Carbonic Anhydrase, Dragon descriptors, Lacosamide derivatives, Molecular docking, QSARAutores:Andrada M.F., Estrada M.R., Martinez J.C.G., Pablo R. Duchowicz, Torrens F., Vega-Hissi E.G.Fuentes:scopusQSAR study and molecular design of open-chain enaminones as anticonvulsant agents
ArticleAbstract: Present work employs the QSAR formalism to pbkp_redict the ED 50 anticonvulsant activity of ringed-ePalabras claves:Anticonvulsant activity, Flexible descriptors, Open-chain enaminone, QSAR TheoryAutores:Castro E.A., Estrada M.R., Martinez J.C.G., Pablo R. Duchowicz, Zamarbide G.N.Fuentes:scopus