Documentos de Muñoz-Torrero D. | REDI

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Mostrando 4 resultados de: 4

Filtros aplicados

Objetivos de Desarrollo Sostenible: "ODS 10: Reducción de las desigualdades"

Subtipo de publicación

Publisher

Journal of Medicinal Chemistry(2)

Journal of Alzheimer's Disease(1)

Área temáticas

Farmacología y terapéutica(4)

Enfermedades(3)

Fisiología humana(1)

Química y ciencias afines(1)

Área de conocimiento

Descubrimiento de fármacos(2)

Farmacología(2)

Neuropsicología(1)

Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar(4)

ODS 9: Industria, innovación e infraestructura(4)

Año de Publicación

Origen

Palabras Claves

Acetylcholinesterase(1)

Cerebellar granule cells(1)

acetylcholinesterase inhibitors(1)

(±)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration

Abstract: Acetylcholinesterase inhibitors (AChEI) are among the drugs most widely used in the treatment of Alz

Palabras claves:

acetylcholinesterase inhibitors, Cerebellar granule cells, colchicine, neuronal death, RAT

Antoni Camins, Camps P., Canudas A.M., Jiménez A., Jordá E.G., Muñoz-Torrero D., Pallás M., Rimbau V., Verdaguer E.

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Abstract: The combination of the scaffolds of the cholinesterase inhibitor huprine Y and the antioxidant capsa

Palabras claves:

Andrisano V., Antoni Camins, Bartolini M., Brazzolotto X., Cieslikiewicz-Bouet M., Cisternas P., Colletier J.P., Coquelle N., De Simone A., Ettcheto M., Firuzi O., García M.L., Inestrosa N.C., Jean L., Muñoz-Torrero D., Nachon F., Oliva C.A., Perez B., Pons M., Renard P.Y., Rendina M., Ricchini M., Sanchez-Lopez E., Saso L., Silman I., Viayna E.

Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation

Abstract: A novel series of donepezil-tacrine hybrids designed to simultaneously interact with the active, per

Palabras claves:

Andrisano V., Antoni Camins, Badia A., Bartolini M., Bidon-Chanal A., Camps P., Clos M.V., Estelrich J., Formosa X., Galdeano C., Gómez T., Lizondo M., Luque F.J., Mancini F., Muñoz-Torrero D., Pallás M., Scarpellini M., Viayna E.

Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates

Abstract: A new family of dual binding site acetylcholinesterase (AChE) inhibitors has been designed, synthesi

Palabras claves:

Acetylcholinesterase, drug design, Inhibitors, β-amyloid peptides, β-secretase

Andrisano V., Antoni Camins, Arce M.P., Badia A., Bartolini M., Bidon-Chanal A., Camps P., Clos M.V., Galdeano C., Gómez T., Junyent F., Luque F.J., Mancini F., Muñoz-Torrero D., Pallás M., Ramírez L., Ratia M., Rodríguez-Franco M.I., Verdaguer E., Viayna E.