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Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites
ReviewAbstract: Malaria is a worldwide disease caused by Plasmodium parasites. A sesquiterpene endoperoxide artemisiPalabras claves:Artemisia annua, Artemisinin, MALARIA, Metabolic engineering, Mode of action, Resistant parasitesAutores:Ery Odette Fukushima, Muangphrom P., Muranaka T., Seki H.Fuentes:googlescopusFunctional analysis of amorpha-4,11-diene synthase (ADS) homologs from non-artemisinin-producing artemisia species: The discovery of novel koidzumiol and (+)-a-Bisabolol synthases
ArticleAbstract: The production of artemisinin, the most effective antimalarial compound, is limited to Artemisia annPalabras claves:(+)-a-Bisabolol, Amorpha-4,11-diene synthase, ARTEMISIA ABSINTHIUM, Artemisia kurramensis, Artemisia maritime, KoidzumiolAutores:Ery Odette Fukushima, Komori A., Mikawa R., Muangphrom P., Muranaka T., Nishiwaki M., Seki H., Suzuki M.Fuentes:googlescopus