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ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
ArticleAbstract: The identification of inflammatory bowel disease (IBD) susceptibility genes by genome-wide associatiPalabras claves:ATG4B, Autophagin-1, Autophagy, COLITIS, Cysteine peptidase, inflammation, Intestinal homeostasis, Paneth cellAutores:Alina Aguirre, Cabrera S., Español Y., Fernández A.F., Freije J.M.P., Fueyo A., Kroemer G., Laurà R., Lõpez-Otín C., Mariño G., Soledad Fernández-García M., Suárez M.F., Vega J.A.Fuentes:scopusLoss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid
ArticleAbstract: MT1-MMP (MMP14) is a collagenolytic enzyme located at the cell surface and implicated in extracellulPalabras claves:aging, extracellular matrix, metalloprotease, Nuclear lamina, retinoidsAutores:Alina Aguirre, Fernández-García M.S., Fueyo A., Garabaya C., Gutiérrez-Abril J., Gutiérrez-Fernández A., Lõpez-Otín C., Osorio F.G., Puente X.S., Soria-Valles C.Fuentes:scopus