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Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations
ReviewAbstract: The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein expPalabras claves:4-phenyl-butyrate, Abcc6, C/EBPβ, Calcification, Generalized arterial calcification in infancy, HNF4α, Pseudoxanthoma elasticumAutores:Arányi T., Brampton C.N., Caroline Bacquet, de Boussac H., Fülöp K., Le Saux O., Pomozi V., Pulaski L., Ratajewski M., Váradi A.Fuentes:scopusStimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters
ArticleAbstract: The ATP-binding cassette G subfamily member ABCG2 protein is involved in drug resistance of variousPalabras claves:ABCG2 promoter variants, Aryl hydrocarbon receptor, BCRP, hepatocellular carcinoma, Oxidative Stress, transcriptionAutores:Arányi T., Brózik A., Caroline Bacquet, de Boussac H., Orbán T.I., Sarkadi B., Tihanyi B., Váradi A., Várady G.Fuentes:scopus