Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

Article

Abstract: The kinetics of the immune changes in COVID-19 across severity groups have not been rigorously asses

Palabras claves:

bystander CD8+ T cell, complement, covid-19, immune pathology, INTERFERÓN, recovery, SARS-COV-2, Systemic inflammation, TNF-α

Autores:

Allison J., Ansaripour A., Baker S., Bergamaschi L., Betancourt A., Bong S.H., Bower G., Bradley J.R., Bucke A., Bullman B., Bunclark K., Butcher H., Calder J., Calero-Nieto F.J., Canna L., Caputo D., Clapham-Riley D., Cossetti C., Coudert J.D., de Bie E.M.D.D., de Sa A., Dewhurst E., di Stefano G., Doffinger R., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fahey C., Fawke S., Fuller S., Furlong A., Gerber P.P., Gleadall N., Goodfellow I.G., Göttgens B., Graf S., Graves B., Gray J., Grenfell R., Gupta R.K., Hanson A.L., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Holmes E., Hosmillo M., Huang C., Huhn O., Hunter K., Ivers T., Jackson S., Jarvis I., Jose S., Josipovic M., Kasanicki M., Kennet J., Kingston N., Kotagiri P., Kourampa J., Laurenti E., Le Gresley E., Legchenko E., Lehner P.J., Lewis D., Linger R., Lyons P.A., Mackay M., Marioni J.C., Marsden J., Martin J., Matara C., Matheson N.J., Meadows A., Meloy S., Mende N., Mescia F., Michael A., Michel R., Morgan M.D., Muldoon F., Mwaura L., Nice F., Nicholson J.K., Petrunkina A.M., Richardson S., Ruffieux H., Saunders C., Smith K.G.C., Thaventhiran J.E.D., Toonen E.J.M., Toshner M., Turner L., Weekes M.P., Wills M.R.

Fuentes:

scopus