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Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence
ReviewAbstract: Chalcones are among the leading bioactive flavonoids with a therapeutic potential implicated to an aPalabras claves:Bioavailability, Chalcones, clinical trials, flavonoids, Molecular mechanisms, Pharmacological studiesAutores:Abdelaali Balahbib, Abdelhakim Bouyahya, Calina D., Constantin Caruntu, Dey A., Docea A.O., Imane Chamkhi, Les F., Leyva-Gomez G., Lopez V., Mehwish Iqbal, Miquel Martorell, Muhammad Akram, Nasreddine El Omari, Quispe C., Salehi B., Sharifi‐rad J.Fuentes:scopusCinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits
ReviewAbstract: The genus Cinnamomum includes a number of plant species largely used as food, food additives and spiPalabras claves:Ciannamomum spp, clinical trials, Mechanisms of action, Pharmacology, phytochemistry, Toxicological dataAutores:Abdelhakim Bouyahya, Anna Abdolshahi, Calina D., Constantin Caruntu, Dey A., Docea A.O., Elena Maria Varoni, Goloshvili T., Iriti M., Koirala N., Les F., Lopez V., Miquel Martorell, Nasreddine El Omari, Nathália Cristina Cirone Silva, Salehi B., Shaheen S., Sharifi‐rad J., Vitalini S.Fuentes:scopusPlant-food-derived Bioactives in Managing Hypertension: From Current Findings to Upcoming Effective Pharmacotherapies
ArticleAbstract: A sedentary lifestyle has evoked a high risk of cardiovascular (CV) disease, diabetes, and obesity,Palabras claves:FATTY ACIDS, functional foods, Hypertension, nutraceuticals, organosulfur compounds, Pharmacological therapies, phenolic compounds, Phytoconstituents, traditional medicineAutores:Alexandra Becherescu, Butnariu M., Deborah Fratantonio, Garsiya Ekaterina Robertovna, Herrera-Bravo J., Ioan Sarac, Iriti M., Kumar M., Les F., Lopez V., Martins N., Miquel Martorell, Pentea M., Setzer W.N., Sharifi‐rad J., Sonal Sukreet, Suleria H.A.R.Fuentes:scopusKCa3.1 transgene induction in murine intestinal epithelium causes duodenal chyme accumulation and impairs duodenal contractility
ArticleAbstract: The epithelial intermediate-conductance calcium/calmodulin-regulated KCa3.1 channel is considered toPalabras claves:Contractility, Duodenum, Epithelium, Intermediate-conductance calcium-activated potassium channel, KCa3.1, Transgenic miceAutores:Calmarza P., Delgado-Wicke P., Esther Pueyo, Garcia-Otin A.L., Hamilton K.L., Köhler R., Lopez V., Lozano-Gerona J., Miura H., Oliván-Viguera A., Ramón-Gimenez M., Valero M.S., Valero S.Fuentes:scopusThe International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
ArticleAbstract: Background: The development of digital technologies and the evolution of open innovation approachesPalabras claves:DIGITAL TOOLS, Hashtag analysis, Natural products, open innovation, Social media, Twitter researchAutores:Abu-Reidah I.M., Aggarwal B.B., Ahmed M.E.O., Akram F., Amira Zarrouk, Arkells N., Babiaka S.B., Badhe P., Banach M., Battino M.A., Bharat B. Aggarwal, Bishayee A., Boyina H.K., Braidy N., Bredt D., Cenanovic M., Chopra H., Cifuentes A., Daniel Sur, De R., Devkota H.P., Dinkova-Kostova A.T., Durazzo A., Echeverría J., Efferth T., El-Demerdash A., Fan T.P., Fiebich B.l., Găman M.A., Gangarapu Kiran, Georgiev M.I., Giampieri F., Gian Luigi Russo, González-Burgos E., Gupta G.K., Gupta S.C., Hammami S., Heinrich M., Horbańczuk J.O., Horbanczuk O.K., Ilkay Erdogan Orhan, Johra Khan, José M. Alvarez-Suarez, Khalid G.M., Khan J., Kharat K.R., Kijjoa A., Kiran G., Lee S., Lizard G., Lonardo S.D., Lopez V., Lordan R., Louka A.M., Lucarini M., Maigoro A.Y., Md Sahab Uddin, Medina C.D.V., Mezzetti B., Miller M.J., Mondal H., Mulholland E.J., Ntie-Kang F., Odimegwu J.I., Oladipupo A.R., Olea S.P., Orhan I.E., Paswan S.K., Patnaik S.S., Perry G., Pittala V., Rajeev K. Singla, Ravanan P., Riaz M., Ronita De, Russo G.L., Sabnani M.K., Sahab Uddin M., Sai C.S., Santini A., Sanusi , Schultz F., Sethiya N.K., Sheridan H., Sheshe S.M., Shrestha B.G., Simal-Gandara J., Singla R.K., Singla S., Sobarzo-Sánchez E., Sonia Hammami, Soojin Lee, Souto E.M.B., Subash Chandra Gupta, Supuran C.T., Sur D., Sureda A., Tai Ping Fan, Thomas Efferth, Tikhonov A., Tomczyk M., Tripathi S.K., Tsagkaris C., Tzvetkov N.T., Ullah H., Urquiza M.S., Vacca R.A., Verma P., Wang D., Wink M., Witkowska A.M., Xiaonan Zheng, Yeung A.W.K., Zarrouk A., Zheng X., Zubair M.A.M.Fuentes:googlescopusThe effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies
ReviewAbstract: Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species including NPalabras claves:apoptosis, Chemopreventive/anticancer agent, Molecular mechanisms, pancreatic cancer, Signaling pathways, ThymoquinoneAutores:Alarcón-Zapata B., Alarcón-Zapata P., Butnariu M., Carla Salgado-Castillo, Cho W.C., Cristian Valdés Vergara, Daştan S.D., Dragunescu A.A., Helon P., Herrera-Bravo J., Koch W., Kukula-Koch W., Les F., Lopez V., Martorell M., Miquel Martorell, Pentea M., Quispe C., Roberts T.H., Samfira I., Sharifi‐rad J., Vergara C.V., William C. Cho, Yessimsiitova Z.Fuentes:googlescopusPaving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder
ReviewAbstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication defiPalabras claves:Autores:Adedayo O. Ademiluyi, Alshehri M.M., Asli Zuluǧ, Butnariu M., Celale Kirkin Gozukirmizi, Ezgi Şenol, Iulia Cristina Bagiu, Kumar M., Les F., Lopez V., Martins N., Olubukola H. Oyeniran, Özçelik B., Quispe C., Semwal P., Sharifi‐rad J., Sharopov F., William C. ChoFuentes:scopusNatural essential oils as a new therapeutic tool in colorectal cancer
ReviewAbstract: Colorectal cancer (CRC) is the third most revalent type of cancer in the world and the second most cPalabras claves:Anticancer properties, Anticancer therapy, apoptosis, Colorectal cancer, cytotoxicity, Natural essential oilsAutores:Alarcón-Zapata B., Alarcón-Zapata P., Calina D., Cásedas G., Dize D., Fokou P.V.T., Garzoli S., Gürer E.S., Iriti M., Javad Sharifi Rad, Les F., Lopez V., Martorell M., Miquel Martorell, Pezzani R., Seitimova G., Sharifi‐rad J., Sharopov F., Vitalini S., Yamthe L.R.T.Fuentes:scopus