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A randomized, double blind, placebo-controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency
ArticleAbstract: GH insensitivity due to GH receptor deficiency is a rare autosomal recessive condition, characterizePalabras claves:Autores:Diamond F.B., Gargosky S.E., Jaime Guevara-Aguirre, Martinez L., Martinez V., Nonoshita L., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusControversy in clinical endocrinology: Reclassification of insulin-like growth factor I production and action disorders
ArticleAbstract: Context: The need for the least ambiguous terminology for disorders affecting IGF-I production and aPalabras claves:Autores:Jaime Guevara-Aguirre, Rosenbloom A.L.Fuentes:scopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusNormal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: A controlled study in a genetically homogeneous population
ArticleAbstract: Superior school performance was reported for 52 Ecuadorian probands with severe deficiency of insuliPalabras claves:Autores:Jaime Guevara-Aguirre, Kranzler J., Martinez V., Rosenbloom A.L.Fuentes:scopusGrowth hormone receptor deficiency in Ecuador
OtherAbstract:Palabras claves:Autores:Francke U., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusGrowth hormone receptor deficiency in ecuador: Clinical and biochemical phenotype in two populations
ArticleAbstract: We have identified 56 patients with GH receptor deficiency (Laron syndrome) from two provinces in soPalabras claves:Autores:Diamond F.B., Fielder P.J., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G.Fuentes:scopusHormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome
ArticleAbstract: Profound growth failure despite elevated GH levels in GH receptor deficiency (GHRD) results from redPalabras claves:Autores:Cohen P., Diamond F.B., Fielder P.J., Gargosky S.E., Jaime Guevara-Aguirre, Rosenbloom A.L., Rosenfeld R.G., Vaccarello M.A., Wilson K.F.Fuentes:scopusTwo-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: Comparison of two dosage levels and to GH-treated GH deficiency
ArticleAbstract: We have reported 1-yr results of a double blind, placebo-controlled trial of recombinant human insulPalabras claves:Autores:Allen L., Gargosky S.E., Jaime Guevara-Aguirre, Martinez V., Rosenbloom A.L., Rosenfeld R.G., Vasconez O.Fuentes:scopusRecommended IGF-I dosage causes greater fat accumulation and osseous maturation than lower dosage and may compromise long-term growth effects
ArticleAbstract: Context: The maximum dose of IGF-I recommended for treatment of GH insensitivity is commonly used. OPalabras claves:Autores:Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosenbloom A.L., Saavedra J.Fuentes:scopusPrismatic case: Bienvenidos a mi tierra de soledad: From poetry to molecular biology in Southern Ecuador
ArticleAbstract:Palabras claves:Autores:Jaime Guevara-Aguirre, Rosenbloom A.L.Fuentes:scopus