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Complexation of daclatasvir by single isomer methylated β-cyclodextrins studied by capillary electrophoresis, NMR spectroscopy and mass spectrometry
ArticleAbstract: In capillary electrophoresis an enantioseparation of daclatasvir (DCV) was observed in case of heptaPalabras claves:capillary electrophoresis, Complex stoichiometry, Complex structure, Cyclodextrin-analyte complexation, Mass spectrometry, nuclear magnetic resonance spectroscopyAutores:Antonio Salgado, Benkovics G., Chankvetadze B., Krait S., Malanga M., Naumann L., Neusüß C., Peluso P., Scriba G.K.E., Sohajda T.Fuentes:scopusIsothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by γ-cyclodextrin and trimethyl-β-cyclodextrin
ArticleAbstract: The complex formation between daclatasvir and γ-CD or heptakis(2,3,6-tri-O-methyl)-β-CD (TM-β-CD) waPalabras claves:Complex stoichiometry, Cyclodextrin complexes, Daclatasvir, isothermal titration calorimetry, Molecular dynamics simulationAutores:Antonio Salgado, Chankvetadze B., Dallocchio R., Dessì A., Krait S., Landy D., Nakhle L., Peluso P., Scriba G.K.E.Fuentes:scopusSeparation of tetrahydrozoline enantiomers in capillary electrophoresis with cyclodextrin-type chiral selectors and investigation of chiral recognition mechanisms
ArticleAbstract: The recognition power and affinity pattern of various cyclodextrins (CD) towards the enantiomers ofPalabras claves:capillary electrophoresis, Chiral recognition mechanism, cyclodextrins, molecular modeling, nuclear magnetic resonance spectroscopy, TetrahydrozolineAutores:Antonio Salgado, Chankvetadze B., Chankvetadze L., Dallocchio R., Gogolashvili A., Lomsadze K., Peluso P., Takaishvili N.Fuentes:scopus