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In vitro neuroprotective and anti-inflammatory activities of natural and semi-synthetic spirosteroid analogues
ArticleAbstract: Two spirosteroid analogues were synthesized and evaluated for their in vitro neuroprotective activitPalabras claves:Excitotoxicity, inflammatory mediators, neuroprotection, SpirosteroidsAutores:Exarchou V., García-Pupo L., Juan Enrique Tacoronte-Morales, Núñez-Figueredo Y., Pieters L., René D.H., Vanden Berghe W., Zaldo-Castro A.Fuentes:scopusMethylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models
ArticleAbstract: Epilepsy is a neurological disease that affects more than 70 million people worldwide and is charactPalabras claves:Drug Discovery, Epilepsy, Methylated flavonoids, mouse, Naringenin, zebrafishAutores:Adriana Orellana-Paucar, Copmans D., De Borggraeve W., De Witte P.A.M., Dehaen W., Exarchou V., Foubert K., Kim Y., Ny A., Pieters L., Siekierska A., Steurs G., Zhang Y.Fuentes:googlescopusPlants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2
ReviewAbstract: COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerPalabras claves:Angiotensin‐converting enzyme inhibitors (ACEi), antiviral, Biomolecules, Coronavirus disease of 2019 (COVID‐19), Medicinal Plants, Middle east respiratory syndrome (MERS), Renin–angiotensin–aldosterone system (RAAS), Severe acute respiratory syndrome coronavirus (SARS‐CoV), Viral entry inhibitorsAutores:Andrea Pino-Acosta, Fabián León-Tamariz, Jaime Alberto Naranjo-Morán, Jeffrey Vargas-Pérez, Juan Manuel Cevallos-Cevallos, Patricia Manzano Santana, Pieters L., Susana Alexandra Llivisaca Contreras, Vanden Berghe W.Fuentes:scopus