Mostrando 10 resultados de: 11
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Journal of Alzheimer's Disease(2)
Molecular Neurobiology(2)
Current Neuropharmacology(1)
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scopus(11)
Epigallocatechin-3-gallate loaded PEGylated-PLGA nanoparticles: A new anti-seizure strategy for temporal lobe epilepsy
ArticleAbstract: Temporal lobe epilepsy is the most common type of pharmacoresistant epilepsy in adults. EpigallocatePalabras claves:Epigallocatechin-3-gallate, Epilepsy, PLGA-PEG, Polymeric nanoparticlesAutores:Antoni Camins, Auladell C., Barenys M., Calpena A.C., Cano A., Espina M., Ettcheto M., Folch J., García M.L., Sanchez-Lopez E.Fuentes:scopusExperimental models for aging and their potential for novel drug discovery
ReviewAbstract: Background: An interesting area of scientific research is the development of potential antiaging druPalabras claves:aging, Heterogeneous mice model, IGF-1, mTOR, Resveratrol, SAMP8, SirtuinsAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pallás M., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusMemantine for the treatment of dementia: A review on its current and future applications
ReviewAbstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the presence in the brainPalabras claves:Alzheimer's disease, Amyloid-protein, Extrasynaptic N-Methyl-D-aspartate receptor, Memantine, Tau proteinAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Olloquequi J., Pelegrí Gabalda C., Sanchez-Lopez E., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusMemantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: In vitro and in vivo characterization
ArticleAbstract: Background: Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown to bePalabras claves:Alzheimer's disease, APPswe/PS1dE9 mice, astrocytes, BEnd.3, Brain targeting, Memantine, Nanoparticles, β-Amyloid plaquesAutores:Antoni Camins, Calpena A.C., Cano A., Carmona N., Egea M.A., Espina M., Ettcheto M., García M.L., Sanchez-Lopez E., Silva A.M., Souto E.M.B.Fuentes:scopusMemantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma
ArticleAbstract: Glaucoma is a multifactorial neurodegenerative disease associated with retinal ganglion cells (RGC)Palabras claves:drug delivery, glaucoma, Memantine, Nanoparticles, PLGA-PEGAutores:Antoni Camins, Calpena A.C., Cordeiro M.F., Davis B.M., Egea M.A., Espina M., Ettcheto M., García M.L., Guo L., Ravindran N., Sanchez-Lopez E., Silva A.M., Souto E.M.B.Fuentes:scopusPeripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
ArticleAbstract: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging arePalabras claves:Alzheimer’s disease, APPswe/PS1dE9, DIABÉTES, high-fat diet, Memantine, obesityAutores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusJNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid
ArticleAbstract: The mitogen-activated protein kinase family (MAPK) is an important group of enzymes involved in cellPalabras claves:Epilepsy, hippocampus, Kainic acid, Licochalcone A, NeurodegenerationAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Verdaguer E., Zárate C.B.Fuentes:scopusReview of the advances in treatment for Alzheimer disease: Strategies for combating β-amyloid protein
OtherAbstract: Introduction Alzheimer disease (AD) is a major neurodegenerative disorder which eventually results iPalabras claves:Alzheimer disease, Amyloid hypotheses, Beta-amyloid, Beta-secretase, Gamma-secretaseAutores:Abad S., Antoni Camins, Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pedros I., Petrov D.Fuentes:scopusThe Ethyl Acetate Extract of Leaves of Ugni molinae Turcz. Improves Neuropathological Hallmarks of Alzheimer's Disease in Female APPswe/PS1dE9 Mice Fed with a High Fat Diet
ArticleAbstract: The most common type of dementia is Alzheimer's disease (AD), a progressive neurodegenerative diseasPalabras claves:APPswe/PS1dE9, ethyl acetate extract, High fat diet, hippocampus, neuroinflammation, Ugni molinaeAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Delporte C., Ettcheto M., Folch J., Jara-Moreno D., Kogan M.J., Verdaguer E.Fuentes:scopus