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Development of a nasal donepezil-loaded microemulsion for the treatment of Alzheimer’s disease: In vitro and Ex vivo characterization
ArticleAbstract: Background: Donepezil (DPZ) is widely prescribed as a specific and reversible acetylcholinesterase iPalabras claves:Alzheimer’s disease, Delivery systems, Donepezil, Intranasal route, Microemulsion, permeationAutores:Calpena A.C., Clares-Naveros B., Fábrega M.J., García M.L., Lupe Carolina Espinoza, Vacacela M.Fuentes:scopusFormulation strategies to improve nose-to-brain delivery of donepezil
ArticleAbstract: Donepezil (DPZ) is widely used in the treatment of Alzheimer’s disease in tablet form for oral adminPalabras claves:Alzheimer’s disease, Donepezil, Mucoadhesion, NANOEMULSIÓN, Nose-to-brain, Pluronic F-127Autores:Calpena A.C., Cañas M.A., Clares-Naveros B., Halbaut L., Lupe Carolina Espinoza, Rodríguez-Lagunas M.J., Silva-Abreu M.Fuentes:scopus