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Inhibition of DNA methyltransferase leads to increased genomic 5-hydroxymethylcytosine levels in hematopoietic cells
ArticleAbstract: 5-Hydroxymethylcytosine (5hmC) is produced from 5-methylcytosine (5mC) by Ten-eleven translocation (Palabras claves:5-aza-2′-deoxycytidine, 5-hydroxymethylcytosine, 5-methylcytosine, Ascorbate, LC-MS/MSAutores:Apró A., Arányi T., Caroline Bacquet, Hathy E., Kiss J., Réthelyi J.M., Szabó P., Szeri F., Szüts D., Vető B.Fuentes:scopusStimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters
ArticleAbstract: The ATP-binding cassette G subfamily member ABCG2 protein is involved in drug resistance of variousPalabras claves:ABCG2 promoter variants, Aryl hydrocarbon receptor, BCRP, hepatocellular carcinoma, Oxidative Stress, transcriptionAutores:Arányi T., Brózik A., Caroline Bacquet, de Boussac H., Orbán T.I., Sarkadi B., Tihanyi B., Váradi A., Várady G.Fuentes:scopusThe transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2
ArticleAbstract: Hepatocyte nuclear factor 4 alpha (HNF4α) nuclear receptor is a master regulator of hepatocyte develPalabras claves:Autores:Arányi T., Bálint B.L., Bojcsuk D., Buday L., Caroline Bacquet, Kiss J., Martin L., Sipeki S., Vető B.Fuentes:scopus