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Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis
ArticleAbstract: Ion channels have recently attracted attention as potential mediators of skin disease. Here, we explPalabras claves:Autores:Abarca-Lachen E., Brown B.M., Delgado-Wicke P., Esther Pueyo, Garcia-Otin A.L., Gilaberte Y., Giraldo P., Hamilton K.L., Juarranz Á., Köhler R., Lozano-Gerona J., Marigil M.Á., Miura H., Oliván-Viguera A., Osada J., Raychaudhuri S.P., Singh V., Surra J.C., Tapia-Casellas E., Valero M.S., Wulff H.Fuentes:scopusPharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes
ArticleAbstract: Background TRPV4 channels are calcium-permeable cation channels that are activated by several physicPalabras claves:Autores:Abarca-Lachen E., Esther Pueyo, Garcia-Malinis A.J., Garcia-Otin A.L., Gilaberte Y., Hamilton K.L., Köhler R., Lozano-Gerona J., Oliván-Viguera A.Fuentes:scopusKCa3.1 transgene induction in murine intestinal epithelium causes duodenal chyme accumulation and impairs duodenal contractility
ArticleAbstract: The epithelial intermediate-conductance calcium/calmodulin-regulated KCa3.1 channel is considered toPalabras claves:Contractility, Duodenum, Epithelium, Intermediate-conductance calcium-activated potassium channel, KCa3.1, Transgenic miceAutores:Calmarza P., Delgado-Wicke P., Esther Pueyo, Garcia-Otin A.L., Hamilton K.L., Köhler R., Lopez V., Lozano-Gerona J., Miura H., Oliván-Viguera A., Ramón-Gimenez M., Valero M.S., Valero S.Fuentes:scopus