Documentos de Smith M.A.

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Mostrando 6 resultados de: 6

Early amyloid accumulation in the hippocampus of SAMP8 mice

Article

Abstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. T

Palabras claves:

aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, Senescence

Autores:

Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.

Fuentes:

scopus

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

Article

Abstract: In earlier studies, we found profound alterations in specific signal transduction pathways such as m

Palabras claves:

ERK, mGluR2, neuroprotection

Autores:

Antoni Camins, Casadesús G., Lee H.g., Nakanishi S., O'Neill M.J., Pallás M., Perry G., Smith M.A., Zhu X.

Fuentes:

scopus

Neuroprotection by c-Jun NH<inf>2</inf>-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry

Article

Abstract: Increasing evidence implicates the c-Jun NH2-terminal kinase (JNK) pathway in the regulation of apop

Palabras claves:

Akt, c-Jun NH2-terminal kinase, cell cycle, Cerebellar granule cells, SP600125

Autores:

Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.

Fuentes:

scopus

Neuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons

Article

Abstract: Glycogen synthase kinase-3 (GSK-3) is involved in the pathogenesis of several neurodegenerative dise

Palabras claves:

B65 Neuroblastoma cells, Cerebellar granule cells, H O 2 2, Lithium, Oxidative Stress, SB-415286

Autores:

Antoni Camins, Casadesús G., Folch J., Pallás M., Pizarro J.G., Rimbau V., Smith M.A., Yeste-Velasco M.

Fuentes:

scopus

Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons

Article

Abstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor o

Palabras claves:

Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +

Autores:

Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.

Fuentes:

scopus

Unveiling "the switch" from aging to Alzheimer's disease with the senescence-accelerated mouse model (SAMP8)

Review

Abstract: Current mouse models of Alzheimer's disease (AD) are restricted to the expression of AD-related path

Palabras claves:

aging, Alzheimer's disease, Amyloid-β, Animal models, COGNITION, Gliosis, Neurodegeneration, Oxidative Stress, SAMP8, Tau phosphorylation

Autores:

Antoni Camins, Casadesús G., Chang J., Kim H.J., Lee H.g., Pallás M., Perry G., Smith M.A., Zhu X.

Fuentes:

scopus

Mostrando 6 resultados de: 6

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Publisher

Área temáticas

Área de conocimiento

Objetivos de Desarrollo Sostenible

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Origen

Palabras Claves

Early amyloid accumulation in the hippocampus of SAMP8 mice

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

Neuroprotection by c-Jun NH<inf>2</inf>-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry

Neuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons

Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons

Unveiling "the switch" from aging to Alzheimer's disease with the senescence-accelerated mouse model (SAMP8)