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Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos
ArticleAbstract: Background IgE is a key mediator of allergic inflammation, and its levels are frequently increased iPalabras claves:admixture mapping, allergy, Asthma, genome-wide association study, Hispanics, IgE, Latinos, minority populations, next-generation sequencingAutores:Adam Davis, Albert M. Levin, Badri Padhukasahasram, Barnes K.C., Benjamin A. Raby, Bleecker E.R., Brian J. O'Roak, Burchard E.G., Bustamante C.D., Carole Ober, Catarina D. Campbell, Cheryl A. Winkler, Chris R. Gignoux, Dan L. Nicolae, Dara G. Torgerson, Denise Serebrisky, Elizabeth A. Nguyen, Emerita Brigino-Buenaventura, Eng C., Evan E. Eichler, Fred Lurmann, Harold J. Farber, Hu D., Huntsman S., Jean G. Ford, Jose Rodriguez-Santana, Joshua Galanter, Karla Sandoval, Katherine K. Nishimura, Kelley Meade, Kiana Mohajeri, L. Keoki Williams, Lindsey A. Roth, Luisa N. Borrell, Martinez F.D., Mathias R.A., Meyers D.A., Michael Lenoir, Moreno-Estrada A., Pedro C. Avila, Pierre Antoine Gourraud, Pino-Yanes M., Rajesh Kumar, Rocio Chapela, Ryan D. Hernandez, Saunak Sen, Shannon Thyne, Steven J. Mack, Weiss S.T., William Rodriguez-CintronFuentes:scopusA genome-wide association study of bronchodilator response in Latinos implicates rare variants
ArticleAbstract: Background The primary rescue medication to treat acute asthma exacerbation is the short-acting β<inPalabras claves:admixture mapping, Asthma, Bronchodilator response, genome-wide association study, Latinos, Rare variantsAutores:Adam Davis, Burchard E.G., Bustamante C.D., Chris R. Gignoux, Dara G. Torgerson, Denise Serebrisky, Emerita Brigino-Buenaventura, Eng C., Fred Lurmann, Harold J. Farber, Huntsman S., Jean G. Ford, Jose Rodriguez-Santana, Joshua Galanter, Karla Sandoval, Katherine A. Drake, Kathleen M. Giacomini, Kelley Meade, Lawrence Lin, Lindsey A. Roth, Luisa N. Borrell, Michael Lenoir, Moreno-Estrada A., Oh S., Pedro C. Avila, Rajesh Kumar, Rocio Chapela, Ryan D. Hernandez, Saunak Sen, Shannon Thyne, Sook Wah Yee, William Rodriguez-CintronFuentes:scopusGenome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: The Genes-environments & Admixture in Latino Americans study
ArticleAbstract: Background Asthma is a complex disease with both genetic and environmental causes. Genome-wide assocPalabras claves:17q21, 6p21, admixture mapping, Asthma, genome-wide association study, Latinos, local ancestryAutores:Adam Davis, Burchard E.G., Bustamante C.D., Cheryl A. Winkler, Chris R. Gignoux, Dara G. Torgerson, Denise Serebrisky, Elizabeth A. Nguyen, Emerita Brigino-Buenaventura, Eng C., Frank Gilliland, Harold J. Farber, Hu D., Huntsman S., Jose Rodriguez-Santana, Joshua Galanter, Karla S. Mendoza, Katherine A. Drake, Kelley Meade, L. Keoki Williams, Lindsey A. Roth, London S., Luisa N. Borrell, Martinez F.D., Michael Lenoir, Moreno-Estrada A., Oh S., Pedro C. Avila, Rajesh Kumar, Romieu I., Saunak Sen, William Klitz, William Rodriguez-CintronFuentes:scopus