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Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe
ArticleAbstract: Genome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier neaPalabras claves:Autores:Albert Zink, Andrea Angius, Andrea Maschio, Andreas Keller, Brenna M. Henn, Bustamante C.D., Carlo Sidore, Chris Jones, Diana Dimitrova, Fabio Busonero, Federico Sánchez-Quinto, Francesco Cucca, Frank Maixner, Georgi Nekhrizov, Gonçalo Abecasis, Ilenia Zara, Javier Mendoza-Revilla, Maristella Pitzalis, Meredith L. Carpenter, Moreno-Estrada A., Nikola Theodossiev, Serena Sanna, Sikora M., Timothy T. Harkins, Underhill P.A.Fuentes:scopusA genome-wide association study of bronchodilator response in Latinos implicates rare variants
ArticleAbstract: Background The primary rescue medication to treat acute asthma exacerbation is the short-acting β<inPalabras claves:admixture mapping, Asthma, Bronchodilator response, genome-wide association study, Latinos, Rare variantsAutores:Adam Davis, Burchard E.G., Bustamante C.D., Chris R. Gignoux, Dara G. Torgerson, Denise Serebrisky, Emerita Brigino-Buenaventura, Eng C., Fred Lurmann, Harold J. Farber, Huntsman S., Jean G. Ford, Jose Rodriguez-Santana, Joshua Galanter, Karla Sandoval, Katherine A. Drake, Kathleen M. Giacomini, Kelley Meade, Lawrence Lin, Lindsey A. Roth, Luisa N. Borrell, Michael Lenoir, Moreno-Estrada A., Oh S., Pedro C. Avila, Rajesh Kumar, Rocio Chapela, Ryan D. Hernandez, Saunak Sen, Shannon Thyne, Sook Wah Yee, William Rodriguez-CintronFuentes:scopusGenome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: The Genes-environments & Admixture in Latino Americans study
ArticleAbstract: Background Asthma is a complex disease with both genetic and environmental causes. Genome-wide assocPalabras claves:17q21, 6p21, admixture mapping, Asthma, genome-wide association study, Latinos, local ancestryAutores:Adam Davis, Burchard E.G., Bustamante C.D., Cheryl A. Winkler, Chris R. Gignoux, Dara G. Torgerson, Denise Serebrisky, Elizabeth A. Nguyen, Emerita Brigino-Buenaventura, Eng C., Frank Gilliland, Harold J. Farber, Hu D., Huntsman S., Jose Rodriguez-Santana, Joshua Galanter, Karla S. Mendoza, Katherine A. Drake, Kelley Meade, L. Keoki Williams, Lindsey A. Roth, London S., Luisa N. Borrell, Martinez F.D., Michael Lenoir, Moreno-Estrada A., Oh S., Pedro C. Avila, Rajesh Kumar, Romieu I., Saunak Sen, William Klitz, William Rodriguez-CintronFuentes:scopusThe genetics of Mexico recapitulates Native American substructure and affects biomedical traits
ArticleAbstract: Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-wide varPalabras claves:Autores:Alejandra V. Contreras, Alessandra Carnevale, Alfredo Hidalgo-Miranda, Alonzo V.A., Andrés Ruiz-Linares, Barquera-Lozano R., Burchard E.G., Bustamante C.D., Canizales-Quinteros S., Chris R. Gignoux, Del Rio Navarro B., Eimear Kenny, Eng C., Fouad Zakharia, Gastón Macín-Pérez, Gerardo Jimenez-Sanchez, Granados J., Huntsman S., Ismael Nuño-Arana, Jean G. Ford, Jose Rodriguez-Santana, Joshua Galanter, Juan Carlos Fernández-López, Juan Jose Sienra-Monge, Karla Sandoval, Karol Estrada, London S., Marc Via, Moreno-Estrada A., Patricia Ortiz-Tello, Rangel-Villalobos H., Rocio Chapela, Rodrigo Garcia-Herrera, Romero-Hidalgo S., Romieu I., Sikora M., Silva-Zolezzi I., Victoria Robles, William Rodriguez-Cintron, Xavier SoberónFuentes:scopus