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Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8
ArticleAbstract: Resveratrol is a polyphenol that is mainly found in grapes and red wine and has been reported to bePalabras claves:Alzheimer's disease, AMPK, Memory impairment, Resveratrol, Senescence, Sirtuin 1, Tau, β-AmyloidAutores:Antoni Camins, Bayod S., Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Porquet D., Sanfeliu C., Vicente A., Vilaplana J.Fuentes:scopusEpigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice
ArticleAbstract: 5XFAD is an early-onset mouse transgenic model of Alzheimer disease (AD). Up to now there are no stuPalabras claves:Alzheimer disease, Behavior, COGNITION, Deacetylase, Methyltransferase, NeurodegenerationAutores:Aguado F., Antoni Camins, Griñan-Ferré C., Ivanova A., Pallás M., Puigoriol-Illamola D., Sanfeliu C., Sarroca S.Fuentes:scopusDysfunction of astrocytes in senescence-accelerated mice SAMP8 reduces their neuroprotective capacity
ArticleAbstract: Early onset increases in oxidative stress and tau pathology are present in the brain of senescence-aPalabras claves:astrocytes, Glutamate uptake, neuroprotection, Oxidative Stress, Senescence-accelerated mice, Tau proteinAutores:Antoni Camins, Coto-Montes A., Cristòfol R., Díez-Vives C., García-Matas S., Gutiérrez-Cuesta J., Pallás M., Rubio-Acero R., Sanfeliu C.Fuentes:scopusNeurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
ArticleAbstract: The senescence-accelerated prone 8 (SAMP8) mouse strain shows early cognitive loss that mimics the dPalabras claves:aging brain, melatonin, Mitochondria, Resveratrol, SAMP8 mouse neuron cultures, Sirtuin 1Autores:Antoni Camins, Corpas R., Coto-Montes A., Cristòfol R., Pallás M., Porquet D., Sanfeliu C., Serret J.Fuentes:scopusResveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway
ArticleAbstract: Metabolic stress induced by high-fat (HF) diet leads to cognitive dysfunction and aging, but the phyPalabras claves:aging, Behavior, COGNITION, Diabetes metabolic stress, Fission, Fusion, Learning, Mitochondria, Mitochondrial dynamics, Neurodegeneration, Resveratrol, β-cateninAutores:Antoni Camins, Canudas A.M., Griñan-Ferré C., Pallás M., Palomera-ávalos V., Puigoriol-Ilamola D., Sanfeliu C.Fuentes:scopusResveratrol modulates response against acute inflammatory stimuli in aged mouse brain
ArticleAbstract: With upcoming age, the capability to fight against harmful stimuli decreases and the organism becomePalabras claves:aging, cytokines, eukaryotic Initiation Factor 2 (eIF2), inflammation, iNOS, mTORAutores:Antoni Camins, Canudas A.M., Griñan-Ferré C., Izquierdo V., Pallás M., Palomera-ávalos V., Sanfeliu C.Fuentes:scopus