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CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes
ArticleAbstract: CD69 is an early activation marker on the surface of T lymphocytes undergoing activation by cognatePalabras claves:CD69, HIF-1α, Hypoxia, tumor microenvironment, tumor-infiltrating lymphocytes (TILs)Autores:Aragonés J., Aznar M.Á., Azpilikueta A., Bolaños E., de la Fuente H., Etxeberria I., Garasa S., Labiano S., Maiso P., Manuel Ortiz de Landázuri, Meléndez-Rodríguez F., Melero I., Molina C., Palazón A., Sánchez-Paulete A.R., Sánchez‐Madrid F., Teijeira A.Fuentes:scopusMutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma
ArticleAbstract: Inactivation of the von Hippel-Lindau (VHL) tumor suppressor drives the development of clear-cell rePalabras claves:Autores:Acosta-Iborra B., Aragonés J., Balsa E., Elorza A., Fuertes-Yebra E., Manuel Ortiz de Landázuri, Ordóñez-NavadijoFuentes:scopusSpecific Oncolytic Effect of a New Hypoxia-Inducible Factor-Dependent Replicative Adenovirus on von Hippel-Lindau-Defective Renal Cell Carcinomas
ArticleAbstract: Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are responsible for a hebkp_reditaryPalabras claves:Autores:Aragonés J., Castellanos M.C., Cuevas Y., Esteban M.A., Hernández-Alcoceba R., Manuel Ortiz de Landázuri, Martin-Puig S., Naranjo-Suárez S., Peso L.D.Fuentes:scopus