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Article(2)
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Farmacología y terapéutica(1)
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Bioquímica(2)
Cytochrome b<inf>5</inf> Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production
ArticleAbstract: Human cytochrome P450 17A1 is required for all androgen biosynthesis and is the target of abirateronPalabras claves:Autores:Im S.C., Pearl N.M., Peng H.M., Rege J., Richard J. Auchus, Turcu A.F., Waskell L.Fuentes:scopusExpression in escherichia coli, purification, and functional reconstitution of human steroid 5α-reductases
ArticleAbstract: The potent androgen 5α-dihydrotestosterone irreversibly derives from testosterone via the activity oPalabras claves:5α-reductase, androgen, Dihydrotestosterone, prostate, steroidogenesisAutores:Han B., Im S.C., Liu J., Peng H.M., Qiao J., Richard J. Auchus, Valentín-Goyco J.Fuentes:scopus