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A genome-wide association study of asthma symptoms in Latin American children
ArticleAbstract: Background: Asthma is a chronic disease of the airways and, despite the advances in the knowledge ofPalabras claves:Asthma symptoms, CHILDREN, Genome-wide association, Latin AmericaAutores:Burchard E.G., Conceição J.S., Costa G.N.O., Del Rio Navarro B., Dudbridge F., Fiaccone R.L., Figueiredo C.A.V., Gouveia M.H., Hancock D.B., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., London S., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Pino-Yanes M., Rodrigues L.C., Rodrigues M.R., Romieu I., Silva T.M., Strina A., Tarazona-Santos E.M.Fuentes:scopusA minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: The Brazilian set
ArticleAbstract: The Brazilian population is considered to be highly admixed. The main contributing ancestral populatPalabras claves:Autores:Esteban N., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Rodrigues M.R., Rodrigues-Soares F., Sanches J.M., Santos H.C., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusGenetic variants in 17q12-21 locus and childhood asthma in Brazil: Interaction with Varicella zoster virus seropositivity
ArticleAbstract: Background: Asthma is a complex disease with worldwide public health relevance, is related to enviroPalabras claves:17q12-21, Atopy, childhood asthma, Varicella zosterAutores:Conceição J.S., Fiaccone R.L., Figueiredo C.A.V., Genser B., Mauricio L. Barreto, Neves N.M.A., Nunes de Oliveira Costa G., Rodrigues L.C., Silva T.M., Strina A.Fuentes:scopusGenomic regions 10q22.2, 17q21.31, and 2p23.1 can contribute to a lower lung function in African descent populations
ArticleAbstract: Accumulated evidence supports the contribution of genetic factors in modulating airway function, espPalabras claves:Admixture mapping strategy, African ancestry, Lung function declineAutores:Araújo N.M., Cruz A.A., Figueiredo C.A.V., Fonseca H.F., Horta B.L., Lima N.P., Mauricio L. Barreto, Rios R., Santolalla M.L., Sant’Anna H.P., Saraiva M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusImpact of FOXP3 gene polymorphisms and gene-environment interactions in asthma and atopy in a Brazilian population
ArticleAbstract: Background: Polymorphisms in genes related to the activation and development of regulatory T cells (Palabras claves:Asthma, Atopy, FOXP3, polymorphismsAutores:Carneiro T.C.B., Carneiro V.L., Costa R.S., de Assis Silva M.F., Figueiredo C.A.V., Fiuza B.S.D., Marques C.R., Mauricio L. Barreto, Neves N.M.A., Silva T.M., Viana W.L.L.Fuentes:scopusReply to Moura et al
OtherAbstract:Palabras claves:Autores:Blanton R.E., Mauricio L. Barreto, Nunes de Oliveira Costa G., Sandhya Rani M.R., Silva T.M.Fuentes:scopusNew variants in NLRP3 inflammasome genes increase risk for asthma and Blomia tropicalis-induced allergy in a Brazilian population
ArticleAbstract: Atopic asthma is a chronic lung disease of lower airways caused mainly due to action of T-helper (ThPalabras claves:allergy, Asthma, CASP1, Inflammasome, NLRP3, VariantsAutores:Costa R.D.S., da Silva R.R., Figueiredo C.A.V., Mauricio L. Barreto, Neves N.M.A., Oliveira S.C., Pires A.d.O., Queiroz G.d.A., Silva T.M.Fuentes:scopusOrigin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
ArticleAbstract: While South Americans are underrepresented in human genomic diversity studies, Brazil has been a claPalabras claves:Bambuí cohort study of ageing, Latin America, Pelotas birth cohort study, Population genetics, Salvador SCAALAAutores:Araujo G.S., Beleza S., Berg D.E., Cabrera L., Costa G.N.O., Debortoli G., Duarte D., Duarte N.E., Fiaccone R.L., Figueiredo C.A.V., Ghirotto S., Gilman R.H., Gonçalves V.F., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Machado M., Magalhães W.C.S., Marrero A.R., Mauricio L. Barreto, Moreira R.G., Muniz Y.C., Pereira A.C., Rodrigues L.C., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santos H.C., Scliar M.O., Silva T.M., Soares-Souza G.B., Tarazona-Santos E.M., Weissensteiner H., Yeager M., Zamudio R.Fuentes:scopus