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[(7-chloroquinolin-4-YL)amino]acetophenones and their copper(II) derivatives: Synthesis, characterization, computational studies and antimalarial activity
ArticleAbstract: The synthesis of the compounds [(7-chloroquinolin-4-yl)amino]acetophenones (4, 5) and their copper(IPalabras claves:Acetophenone, Antimalarial, Copper, DFT, fragmentation, quinolineAutores:Acosta M.E., Charris J.E., Colmenarez J.B., Félix Andueza, Ferrer M R.E., Gut J., Rosenthal P.J., Yonathan De J. ParraFuentes:scopusSynthesis and in silico ADME/Tox profiling studies of heterocyclic hybrids based on chloroquine scaffolds with potential antimalarial activity
ArticleAbstract: A series of heterocyclic chloroquine hybrids containing either a β-phenethylamine fragment or a 2-amPalabras claves:2-Aminoindane, Chloroquine, Hemozoin, MALARIA, β-PhenethylamineAutores:Ángel J.E., Charris J.E., Esteban Fernández-Moreira, Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis of trans- and cis-2-acetyl-3-phenyl-3,3a,4,5-tetrahydro-2H-benzo[g] indazoles: evaluation as inhibitors of β-hematin formation
ArticleAbstract: Several trans- and cis-2-acetyl-3-(substituted-phenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazole derivPalabras claves:Diastereomers, Hydrazine, Indazoles, MALARIA, Pyrazolines, Β-hematinAutores:Acosta M.E., Ángel J.E., Aparicio D.A., Charris J.E., Llovera L.J., Lobo G.M., Lola De Lima, Monasterios M.C., Sanchez J.L.Fuentes:scopusSynthesis, characterization, crystal structure and antimalarial activity of (2E)-2-(1-{4-[(7-chloroquinolin-4-yl)amino]phenyl} ethylidene)hydrazine carbothioamide
ArticleAbstract: A simple synthesis and study by UV-vis, IR, NMR, ESI-CID-MS2 and X-ray diffraction of ((2E)-2-(1-{4-Palabras claves:Antimalarial activity, Crystal structure, ThiosemicarbazonesAutores:Bruno-Colmenarez J., Charris J.E., De Domínguez N.G., Ferrer R., Gut J., Lobo G.M., Rosenthal P.J., Yonathan De J. ParraFuentes:scopus