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Synthesis and in silico ADME/Tox profiling studies of heterocyclic hybrids based on chloroquine scaffolds with potential antimalarial activity
ArticleAbstract: A series of heterocyclic chloroquine hybrids containing either a β-phenethylamine fragment or a 2-amPalabras claves:2-Aminoindane, Chloroquine, Hemozoin, MALARIA, β-PhenethylamineAutores:Ángel J.E., Charris J.E., Esteban Fernández-Moreira, Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis of trans- and cis-2-acetyl-3-phenyl-3,3a,4,5-tetrahydro-2H-benzo[g] indazoles: evaluation as inhibitors of β-hematin formation
ArticleAbstract: Several trans- and cis-2-acetyl-3-(substituted-phenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazole derivPalabras claves:Diastereomers, Hydrazine, Indazoles, MALARIA, Pyrazolines, Β-hematinAutores:Acosta M.E., Ángel J.E., Aparicio D.A., Charris J.E., Llovera L.J., Lobo G.M., Lola De Lima, Monasterios M.C., Sanchez J.L.Fuentes:scopus