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Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis
ArticleAbstract: The HLH-2004 criteria are used to diagnose hemophagocytic lymphohistiocytosis (HLH), yet concern exiPalabras claves:Autores:Abhyankar H.A., Al-Herz W., Aldave-Becerra J.C., Allen C.E., Bashir D.A., Cao T.N., Cecilia Poli M., Chamdin A., Chinn I.K., Coban-Akdemir Z.H., Diaz M.I., Eckstein O.S., Forbes L.R., Gibbs R.A., Goldberg B.R., Goldman J.R., Heslop H.E., Hong D.N., Jhangiani S.N., Krance R.A., Luis Alberto Pedroza, Lupski J.R., Mace E.M., Martinez C.A., McClain K.L., McGhee S.A., Muzny D.M., Nguyen T.C., Nicholas S.K., Orange J.S., Peckham-Gregory E.C., Stray-Pedersen A., Vogel T.P.Fuentes:scopusSchistosomiasis induces persistent DNA methylation and tuberculosis-specific immune changes
ArticleAbstract: Epigenetic mechanisms, such as DNA methylation, determine immune cell phenotype. To understand the ePalabras claves:Autores:Bhalla K.N., Coarfa C., DiNardo A.R., Graviss E.A., Kay A.W., Mace E.M., Makedonas G., Mandalakas A.M., Maphalala G., Mtetwa G., Nishiguchi T., Orange J.S., Rajapakshe K., Rojelio Mejia, Secor W.E.Fuentes:scopusPro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING
ArticleAbstract: The cellular sensor stimulator of interferon genes (STING) initiates type I interferon (IFN) and cytPalabras claves:AMPK inhibitor, Autoimmune Disease, gain-of-function mutation, inflammatory disease, Sting, STING inhibitor, type I interferonopathy, ULK1 phosphorylationAutores:Alejandra Mendoza, Barber G.N., Chinn I.K., Hong D.N., Konno H., Luis Alberto Pedroza, Lupski J.R., Orange J.S.Fuentes:scopusThe role of AIRE in the immunity against Candida albicans in a model of human macrophages
ArticleAbstract: Autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a primary immunodeficiencPalabras claves:AIRE, APECED, c. albicans, Dectin receptor, Hyphae, Macrophages, Receptor recruitmentAutores:Arslanian C., Banerjee P.P., Barbosa-Carvalho M.U.W., Câmara N.O.S., Castold A., Condino-Neto A., Correia-Deur J.E.d.M., de Albuquerque J.A.T., Dias-da-Silva M.R., Lazaretti-Castro M., Luis Alberto Pedroza, Ma R., Mace E.M., Orange J.S., Weiler F.G., Ynoue L.H., Zurro N.B.Fuentes:scopus