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scopus(11)
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
ArticleAbstract: Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to theirPalabras claves:Alzheimer's disease, benzodiazepines, COGNITION, dementia, RISK FACTORSAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusC-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusA single dose of pirfenidone attenuates neuronal loss and reduces lipid peroxidation after kainic acid-induced excitotoxicity in the pubescent rat hippocampus
ArticleAbstract: Systemic administration of kainic acid (KA) in rodents triggers limbic seizures following selectivePalabras claves:4-Hydroxynonenal (4-HNE), Kainic Acid Model, Neurodegeneration, neuroprotection, PirfenidoneAutores:Antoni Camins, Armendáriz-Borunda J., Bañuelos-Pineda J., Castro-Torres R.D., Chaparro-Huerta V., Flores-Soto M.E., Orozco-Suárez S.A., Zárate C.B.Fuentes:scopusNeuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms
ArticleAbstract: The activation of c-Jun-N-terminal kinases (JNK) pathway has been largely associated with the pathogPalabras claves:c-Jun N-terminal kinase, Excitotoxicity, hippocampus, inflammation, Kainic acid, Knockout mice, Neurodegeneration, neuroprotectionAutores:Antoni Camins, Auladell C., Castro-Torres R.D., De Lemos M.L., Folch J., Junyent F., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopusP38 MAPK Inhibition Protects Against Glutamate Neurotoxicity and Modifies NMDA and AMPA Receptor Subunit Expression
ArticleAbstract: NMDA and AMPA receptors are thought to be responsible for Ca++ influx during glutamate-induced excitPalabras claves:Cell signaling, Excitotoxicity, Glu-R expression, glutamate, p38 MAPKAutores:Antoni Camins, Castañeda-Arellano R., Castro-Torres R.D., Gudiño-Cabrera G., Rivera-Cervantes M.C., y Velasco A.I.F., Zárate C.B.Fuentes:scopusMemantine for the treatment of dementia: A review on its current and future applications
ReviewAbstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the presence in the brainPalabras claves:Alzheimer's disease, Amyloid-protein, Extrasynaptic N-Methyl-D-aspartate receptor, Memantine, Tau proteinAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Olloquequi J., Pelegrí Gabalda C., Sanchez-Lopez E., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusPirfenidone Attenuates Microglial Reactivity and Reduces Inducible Nitric Oxide Synthase mRNA Expression After Kainic Acid-Mediated Excitotoxicity in Pubescent Rat Hippocampus
ArticleAbstract: Excitotoxicity and neuroinflammation are strongly linked to the progressions of neurodegenerative diPalabras claves:cytokines, iNOS, Kainic acid, Microglial reactivity, PirfenidoneAutores:Antoni Camins, Armendáriz-Borunda J., Castro-Torres R.D., Chaparro-Huerta V., Flores-Soto M.E., Jave-Suárez L., Mena-Munguía S., Zárate C.B.Fuentes:scopusInvolvement of JNK1 in Neuronal Polarization During Brain Development
ReviewAbstract: The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control oPalabras claves:asymmetric division, DCX, JNK1, MAP1B, MIGRATION, NMDAR, SCG10, synaptogenesis, WDR62Autores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Olloquequi J., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusJNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy
ArticleAbstract: Neurogenesis in the adult dentate gyrus (DG) of the hippocampus allows the continuous generation ofPalabras claves:adult hippocampal neurogenesis, JNK isoforms, Kainic acid, Knockout miceAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Landa J., Olloquequi J., Rabaza M., Verdaguer E., Zárate C.B.Fuentes:scopusJNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid
ArticleAbstract: The mitogen-activated protein kinase family (MAPK) is an important group of enzymes involved in cellPalabras claves:Epilepsy, hippocampus, Kainic acid, Licochalcone A, NeurodegenerationAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Verdaguer E., Zárate C.B.Fuentes:scopus