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Cirrhosis induced by thioacetamide is prevented by stevia. Molecular mechanisms
ArticleAbstract: This study aimed to investigate the ability of stevia leaves to prevent thioacetamide (TAA)-inducedPalabras claves:Anti-Inflammatory, FIBROSIS, Liver, Stevioside, sweetenerAutores:Casas-Grajales S., Diaz-Ruiz A., Flores-Beltrán R.E., Galindo-Gómez S., Hernández-Aquino E., Javier Camacho, Montes S., Muriel P., Ramos-Tovar E., Tsutsumi V., Vera-Aguilar E.Fuentes:scopusAn aqueous extract of Stevia rebaudiana variety Morita II prevents liver damage in a rat model of cirrhosis that mimics the human disease
ArticleAbstract: Introduction and aim: Stevia has exhibited antioxidant, antihyperglycemic, antihypertensive and antiPalabras claves:Anti-Inflammatory, Antifibrotic, antioxidant, FIBROSIS, hepatic stellate cellAutores:Flores-Beltrán R.E., Galindo-Gómez S., Javier Camacho, Muriel P., Ramos-Tovar E., Tsutsumi V.Fuentes:scopusAntioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays
ArticleAbstract: Aims: Stevioside is a diterpenoid obtained from the leaves of Stevia rebaudiana (Bertoni) that exhibPalabras claves:Cocultures, docking, Immunomodulatory, Nrf2, Stevioside, TAAAutores:Alvarez-Suarez D.E., Casas-Grajales S., Cerda-García-Rojas C.M., Chávez-Estrada E., Hernández-Aquino E., Javier Camacho, Lakshman M.R., Muriel P., Ramos-Tovar E., Reyes-Gordillo K., Tsutsumi V.Fuentes:scopusQuercetin reverses experimental cirrhosis by immunomodulation of the proinflammatory and profibrotic processes
ArticleAbstract: The ability of quercetin to reverse an established cirrhosis has not yet been investigated. ThereforPalabras claves:CCl 4, Cirrhosis, FIBROSIS, Hepatic stellate cells, HepG2, quercetin, TGF-β, thioacetamideAutores:Casas-Grajales S., Cerda-García-Rojas C.M., Flores-Beltrán R.E., Hernández-Aquino E., Javier Camacho, Muriel P., Ramos-Tovar E., Shibayama M., Tsutsumi V., Vázquez-Flores L.Fuentes:scopusStevia prevents acute and chronic liver injury induced by carbon tetrachloride by blocking oxidative stress through Nrf2 upregulation
ArticleAbstract: The effect of stevia on liver cirrhosis has not been previously investigated. In the present study,Palabras claves:Autores:Buendia-Montaño L., Casas-Grajales S., Galindo-Gómez S., Hernández-Aquino E., Javier Camacho, Muriel P., Ramos-Tovar E., Tsutsumi V.Fuentes:scopusStevia rebaudiana tea prevents experimental cirrhosis via regulation of NF-κB, Nrf2, transforming growth factor beta, Smad7, and hepatic stellate cell activation
ArticleAbstract:Palabras claves:Anti-Inflammatory, antioxidant, Encephalopathy, FIBROSIS, Liver, SteviaAutores:Diaz-Ruiz A., Flores-Beltrán R.E., Galindo-Gómez S., Javier Camacho, Montes S., Muriel P., Ramos-Tovar E., Tsutsumi V., Vera-Aguilar E.Fuentes:scopusStevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation
ArticleAbstract: Liver cirrhosis is associated with increased morbidity and mortality with important health and sociaPalabras claves:Co-culture, FIBROSIS, hepatic stellate cell, Smad, SteviosideAutores:Alvarez-Suarez D.E., Casas-Grajales S., Dayana Buendía-Montaño L., Javier Camacho, Lakshman M.R., Muriel P., Ramos-Tovar E., Reyes-Gordillo K., Tsutsumi V.Fuentes:scopus