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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(1)
Current Issues in Molecular Biology(1)
Current Medicinal Chemistry(1)
Drug Development Research(1)
Elsevier B.V.(1)
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Farmacología y terapéutica(8)
Bioquímica(5)
Enfermedades(4)
Microorganismos, hongos y algas(4)
Vertebrados de sangre fría(2)
Traditional and Computational Screening of Non-Toxic Peptides and Approaches to Improving Selectivity
ReviewAbstract: Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or diagnostic toPalabras claves:hemolysis, IN SILICO, Machine Learning, Peptides, toxicityAutores:Alberto A. Robles-Loaiza, Bruno Mendes, Carolina Proaño-Bolaños, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., Jose Rafael de Almeida, Josselyn A. Ortega-Pila, Plisson F., Teixeira C.A.S.Fuentes:googleorcidscopusSnake Venom Peptides and Low Mass Proteins: Molecular Tools and Therapeutic Agents
ArticleAbstract: Snake venoms are natural sources of biologically active molecules that are able to act selectively aPalabras claves:Bradykinin-potentiating peptide, Crotamine, Disintegrin, Natriuretic peptide, Sarafotoxin, Three-finger toxinAutores:Caldeira C.A.S., Carregari V.C., Coutinho-Neto A., de Azevedo Calderon L., Gomes P.A.D.C., Huancahuire-Vega S., Jose Rafael de Almeida, Marangoni S., R. K. Watanabe, Resende L.M., Saulo L. Silva, Soares A.M., Valed N.Fuentes:googleorcidscopusHarnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance
ArticleAbstract: The emergence of antibiotic resistance drives an essential race against time to reveal new molecularPalabras claves:antibacterial peptides, antibiotic-resistant bacteria, Peptidomimetics, Phospholipase A 2, Snake venomAutores:Antonio L.V. Palacios, Bruno Mendes, Gomes P.A.D.C., Jose Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. Silva, Teixeira C.A.S.Fuentes:googleorcidscopusA novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Phospholipase A2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., Jose Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusPeptides to Tackle Leishmaniasis: Current Status and Future Directions
ArticleAbstract: Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by the pharmaPalabras claves:Amastigote, Drug Discovery, Leishmania spp, Peptides, PromastigoteAutores:Alberto A. Robles-Loaiza, Alejandro Pinos-Tamayo, Alves C., Bruno Mendes, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., Jose Rafael de Almeida, Teixeira C.A.S.Fuentes:googleorcidscopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A2-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., Jose Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusUnlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad
ArticleAbstract: Malaria, leishmaniasis and Chagas disease are vector-borne protozoal infections with a disproportionPalabras claves:Peptides, Snake venoms, Vector-borne protozoan infectionsAutores:Ana Gomes, Bruno Mendes, David Salazar-Valenzuela, Denise Duarte, Fátima Nogueira, Gomes P.A.D.C., Jose Rafael de Almeida, Luísa Aguiar, Mariana Borges Costa Brioschi, Mariana Ferreira, Miguel D.C., Paula Gameiro, Sofia Cortes, Teixeira C.A.S.Fuentes:googleorcidscopusFirst Bioprospecting Study of Skin Host-Defense Peptides in Odontophrynus americanus
ArticleAbstract: The adaptation of amphibians to diverse environments is closely related to the characteristics of thPalabras claves:Autores:Alberício F., B. G. De la Torre, Basso N.G., Cancelarich N.L., Eder A. Barbosa, Gomes P.A.D.C., Leite J.R., Marani M.M., Miriam Arrulo, Moreira D.C., Pérez L.O., Peter Eaton, Sariah Trillo Gugliotti, Teixeira C.A.S.Fuentes:scopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A<inf>2</inf> toxins present in snake venoms interact with biological membranes and sePalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., Jose Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:googleorcidscopus