Mostrando 10 resultados de: 33
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Pharmacogenomics(3)
Drug Metabolism and Drug Interactions(2)
Nature Communications(2)
Revista de Biologia Tropical(2)
Scientific Reports(2)
Challenges and Opportunities for Clinical Pharmacogenetic Research Studies in Resource-limited Settings: Conclusions From the Council for International Organizations of Medical Sciences–Ibero-American Network of Pharmacogenetics and Pharmacogenomics Meeting
ArticleAbstract: Purpose: The symposium Health and Medicines in Indigenous Populations of America was organized by thPalabras claves:CIOMS-RIBEF, clinical research, pharmacogenetics, resource-limited settingsAutores:Adrián LLerena, Diwakar S., Enrique Terán, Galaviz-Hernandez C., Gil J.P., Isabel Hernández, Lara-Riegos J., Molina-Guarneros J.A., Moya G.E., Nair S., Penãs-Lledó E.M., Rägo L., Ramírez-Roa R., Sosa-Macías M.G., Tarazona-Santos E.M., Verde I.Fuentes:googlescopusAuthor Correction: Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil (Nature Communications, (2022), 13, 1, (1004), 10.1038/s41467-022-28648-3)
OtherAbstract: The original version of this Article contained an error in the title, which was previously incorrectPalabras claves:Autores:Araújo N.M., Borda V., Bozoklian D., Buzzo J.L., Cáceres O., Castelli E.C., Castro C.F.B., Ceroni J.R.M., da Silva Simões C.E., da Silva Souza A., de Carvalho D.L., de Souza Andrade H., Dean M., dos Santos Brito Silva N., Duarte Y.A.O., Galante P.A.F., Guio H., Guryev V., Horta B.L., Karp T., Lima-Costa M.F., Magalhães W.C.S., Mauricio L. Barreto, Mendes-Junior C.T., Mercuri R.L.V., Meyer D., Miller T.L.A., Mingroni-Netto R.C., Naslavsky M.S., Nonaka R., Nunes K., Passos M.R.S., Passos-Bueno M.R., Rego F.O., Rojas C.P., Sanchez C., Scliar M.O., Tarazona-Santos E.M., Wang J.Y.T., Yamamoto G.L., Zatz M., Zverinova S.Fuentes:scopusBiogeographical ancestry is associated with socioenvironmental conditions and infections in a Latin American urban population
ArticleAbstract: Racial inequalities are observed for different diseases and are mainly caused by differences in sociPalabras claves:biogeographical ancestry, Infections, racial inequalities, Socioeconomic statusAutores:Costa G.N.O., Fiaccone R.L., Figueiredo C.A.V., Kehdy F.S.G., Mauricio L. Barreto, Neves N.M.A., Rodrigues L.C., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusA genome-wide association study of asthma symptoms in Latin American children
ArticleAbstract: Background: Asthma is a chronic disease of the airways and, despite the advances in the knowledge ofPalabras claves:Asthma symptoms, CHILDREN, Genome-wide association, Latin AmericaAutores:Burchard E.G., Conceição J.S., Costa G.N.O., Del Rio Navarro B., Dudbridge F., Fiaccone R.L., Figueiredo C.A.V., Gouveia M.H., Hancock D.B., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., London S., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Pino-Yanes M., Rodrigues L.C., Rodrigues M.R., Romieu I., Silva T.M., Strina A., Tarazona-Santos E.M.Fuentes:scopusA minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: The Brazilian set
ArticleAbstract: The Brazilian population is considered to be highly admixed. The main contributing ancestral populatPalabras claves:Autores:Esteban N., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Rodrigues M.R., Rodrigues-Soares F., Sanches J.M., Santos H.C., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusAdmixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
ArticleAbstract: Background/objectives: Admixed populations are a resource to study the global genetic architecture oPalabras claves:Autores:Alvim I.O., Araujo G.S., Araújo N.M., Borda V., Choudhury A., Duarte Y.A.O., Dutil J., Gilman R.H., Gouveia M.H., Guio H., Hansen M.E.B., Horta B.L., Hsing A.W., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Lobo F., Luizon M.R., Lyra R., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Mensah J., Michelin L.A., Naslavsky M.S., Norris S.A., O´Connor T.D., Passos-Bueno M.R., Peixoto S.V., Pereira A.C., Ramsay M., Rodrigues M.R., Santolalla M.L., Sant’Anna H.P., Scliar M.O., Tarazona-Santos E.M., Tishkoff S.A., Yamamoto G.L., Yeager M., Yeboah E., Zatz M., Zolini C.Fuentes:scopusAfrican biogeographical ancestry, atopic and non-atopic asthma and atopy: A study in Latin American children
ArticleAbstract: Background: Genetic variants underlying African ancestry have been suggested be implicated in the etPalabras claves:allergy, Asthma, biogeographical ancestry, Mediation, racial inequalitiesAutores:Costa G.N.O., Cruz A.A., Fattore G.L., Feitosa C.A., Fiaccone R.L., Figueiredo C.A.V., Kehdy F.S.G., Mauricio L. Barreto, Neves N.M.A., Rodrigues L.C., Santos D.N., Santos L.M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusGenetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative
ArticleAbstract: We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil, and their dPalabras claves:Autores:Adrián LLerena, Andrade P.X.C., Aquino M.M., Céspedes-Garro C., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Pereira A.C., Rodrigues-Soares F., Sampaio-Coelho J., Tarazona-Santos E.M., Zolini C.Fuentes:scopusGenome-wide burden and association analyses implicate copy number variations in asthma risk among children and young adults from Latin America
ArticleAbstract: The genetic architecture of asthma was relatively well explored. However, some work remains in the fPalabras claves:Autores:Barbosa G.C.G., Costa G.N.O., Damasceno A.K.A., Fiaccone R.L., Figueiredo C.A.V., Hartwig F.P., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Oliveira P.R.S., Pereira A.C., Ribeiro-Silva R.D.C., Rodrigues L.C., Tarazona-Santos E.M.Fuentes:scopusGenomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
ArticleAbstract: We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and pbkp_redicted phenotypes inPalabras claves:Autores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Francisco J.López Hernández, Fricke-Galindo I., Galaviz-Hernandez C., Garza-Ocañas L., Gilman R.H., Grazina M., Humberto Fariñas, Jiménez-Arce G., Jung-Cook H., Lares-Aseff I., Lazalde-Ramos B.P., López-López M., Michelin L.A., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rodrigues-Soares F., Rojas-Martinez A., Santiago Terán, Sarmiento A.P., Scliar M.O., Sosa-Macías M.G., Tarazona-Santos E.M., Tinoco C.A., Zamudio R.Fuentes:googlescopus