Mostrando 10 resultados de: 23
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Author Correction: Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil (Nature Communications, (2022), 13, 1, (1004), 10.1038/s41467-022-28648-3)
OtherAbstract: The original version of this Article contained an error in the title, which was previously incorrectPalabras claves:Autores:Araújo N.M., Borda V., Bozoklian D., Buzzo J.L., Cáceres O., Castelli E.C., Castro C.F.B., Ceroni J.R.M., da Silva Simões C.E., da Silva Souza A., de Carvalho D.L., de Souza Andrade H., Dean M., dos Santos Brito Silva N., Duarte Y.A.O., Galante P.A.F., Guio H., Guryev V., Horta B.L., Karp T., Lima-Costa M.F., Magalhães W.C.S., Mauricio L. Barreto, Mendes-Junior C.T., Mercuri R.L.V., Meyer D., Miller T.L.A., Mingroni-Netto R.C., Naslavsky M.S., Nonaka R., Nunes K., Passos M.R.S., Passos-Bueno M.R., Rego F.O., Rojas C.P., Sanchez C., Scliar M.O., Tarazona-Santos E.M., Wang J.Y.T., Yamamoto G.L., Zatz M., Zverinova S.Fuentes:scopusA genome-wide association study of asthma symptoms in Latin American children
ArticleAbstract: Background: Asthma is a chronic disease of the airways and, despite the advances in the knowledge ofPalabras claves:Asthma symptoms, CHILDREN, Genome-wide association, Latin AmericaAutores:Burchard E.G., Conceição J.S., Costa G.N.O., Del Rio Navarro B., Dudbridge F., Fiaccone R.L., Figueiredo C.A.V., Gouveia M.H., Hancock D.B., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., London S., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Pino-Yanes M., Rodrigues L.C., Rodrigues M.R., Romieu I., Silva T.M., Strina A., Tarazona-Santos E.M.Fuentes:scopusA minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: The Brazilian set
ArticleAbstract: The Brazilian population is considered to be highly admixed. The main contributing ancestral populatPalabras claves:Autores:Esteban N., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Rodrigues M.R., Rodrigues-Soares F., Sanches J.M., Santos H.C., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusAdmixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
ArticleAbstract: Background/objectives: Admixed populations are a resource to study the global genetic architecture oPalabras claves:Autores:Alvim I.O., Araujo G.S., Araújo N.M., Borda V., Choudhury A., Duarte Y.A.O., Dutil J., Gilman R.H., Gouveia M.H., Guio H., Hansen M.E.B., Horta B.L., Hsing A.W., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Lobo F., Luizon M.R., Lyra R., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Mensah J., Michelin L.A., Naslavsky M.S., Norris S.A., O´Connor T.D., Passos-Bueno M.R., Peixoto S.V., Pereira A.C., Ramsay M., Rodrigues M.R., Santolalla M.L., Sant’Anna H.P., Scliar M.O., Tarazona-Santos E.M., Tishkoff S.A., Yamamoto G.L., Yeager M., Yeboah E., Zatz M., Zolini C.Fuentes:scopusGenetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative
ArticleAbstract: We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil, and their dPalabras claves:Autores:Adrián LLerena, Andrade P.X.C., Aquino M.M., Céspedes-Garro C., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Pereira A.C., Rodrigues-Soares F., Sampaio-Coelho J., Tarazona-Santos E.M., Zolini C.Fuentes:scopusGenome-wide burden and association analyses implicate copy number variations in asthma risk among children and young adults from Latin America
ArticleAbstract: The genetic architecture of asthma was relatively well explored. However, some work remains in the fPalabras claves:Autores:Barbosa G.C.G., Costa G.N.O., Damasceno A.K.A., Fiaccone R.L., Figueiredo C.A.V., Hartwig F.P., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Oliveira P.R.S., Pereira A.C., Ribeiro-Silva R.D.C., Rodrigues L.C., Tarazona-Santos E.M.Fuentes:scopusGenomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
ArticleAbstract: We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and pbkp_redicted phenotypes inPalabras claves:Autores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Francisco J.López Hernández, Fricke-Galindo I., Galaviz-Hernandez C., Garza-Ocañas L., Gilman R.H., Grazina M., Humberto Fariñas, Jiménez-Arce G., Jung-Cook H., Lares-Aseff I., Lazalde-Ramos B.P., López-López M., Michelin L.A., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rodrigues-Soares F., Rojas-Martinez A., Santiago Terán, Sarmiento A.P., Scliar M.O., Sosa-Macías M.G., Tarazona-Santos E.M., Tinoco C.A., Zamudio R.Fuentes:googlescopusGenomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative)
ArticleAbstract: Brazil never had segregation laws defining membership of an ethnoracial group. Thus, the compositionPalabras claves:Autores:Gouveia M.H., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mambrini J., Mauricio L. Barreto, Pereira A.C., Rodrigues L.C., Rodrigues-Soares F., Tarazona-Santos E.M., Victora C.G.Fuentes:scopusGenomic regions 10q22.2, 17q21.31, and 2p23.1 can contribute to a lower lung function in African descent populations
ArticleAbstract: Accumulated evidence supports the contribution of genetic factors in modulating airway function, espPalabras claves:Admixture mapping strategy, African ancestry, Lung function declineAutores:Araújo N.M., Cruz A.A., Figueiredo C.A.V., Fonseca H.F., Horta B.L., Lima N.P., Mauricio L. Barreto, Rios R., Santolalla M.L., Sant’Anna H.P., Saraiva M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusEthnic background and CYP2D6 genetic polymorphisms in Costa Ricans
ArticleAbstract: CYP2D6 differences have already been demonstrated within Latin American populations by the CEIBA.FPPalabras claves:Afro-Caribbean, Amerindian, COSTA RICA, CYP2D6, MESTIZO, Poor metabolizers, populations, Ultrarapid metabolizersAutores:Adrián LLerena, Barrantes R., Calzadilla L.R., Céspedes-Garro C., Enrique Terán, Estévez-Carrizo F.E., Grazina M., Jiménez-Arce G., López-López M., María-Eugenia G.N., Moya G.E., Ortiz-López R., Ramírez-Roa R., Rodeiro I., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M.Fuentes:scopus