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Revista de Biologia Tropical(2)
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Clinical Pharmacology and Therapeutics(1)
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European Journal of Human Genetics(1)
A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: The Brazilian set
ArticleAbstract: The Brazilian population is considered to be highly admixed. The main contributing ancestral populatPalabras claves:Autores:Esteban N., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Rodrigues M.R., Rodrigues-Soares F., Sanches J.M., Santos H.C., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusGenetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative
ArticleAbstract: We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil, and their dPalabras claves:Autores:Adrián LLerena, Andrade P.X.C., Aquino M.M., Céspedes-Garro C., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Pereira A.C., Rodrigues-Soares F., Sampaio-Coelho J., Tarazona-Santos E.M., Zolini C.Fuentes:scopusGenomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
ArticleAbstract: We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and pbkp_redicted phenotypes inPalabras claves:Autores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Francisco J.López Hernández, Fricke-Galindo I., Galaviz-Hernandez C., Garza-Ocañas L., Gilman R.H., Grazina M., Humberto Fariñas, Jiménez-Arce G., Jung-Cook H., Lares-Aseff I., Lazalde-Ramos B.P., López-López M., Michelin L.A., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rodrigues-Soares F., Rojas-Martinez A., Santiago Terán, Sarmiento A.P., Scliar M.O., Sosa-Macías M.G., Tarazona-Santos E.M., Tinoco C.A., Zamudio R.Fuentes:googlescopusGenomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative)
ArticleAbstract: Brazil never had segregation laws defining membership of an ethnoracial group. Thus, the compositionPalabras claves:Autores:Gouveia M.H., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mambrini J., Mauricio L. Barreto, Pereira A.C., Rodrigues L.C., Rodrigues-Soares F., Tarazona-Santos E.M., Victora C.G.Fuentes:scopusGenomic regions 10q22.2, 17q21.31, and 2p23.1 can contribute to a lower lung function in African descent populations
ArticleAbstract: Accumulated evidence supports the contribution of genetic factors in modulating airway function, espPalabras claves:Admixture mapping strategy, African ancestry, Lung function declineAutores:Araújo N.M., Cruz A.A., Figueiredo C.A.V., Fonseca H.F., Horta B.L., Lima N.P., Mauricio L. Barreto, Rios R., Santolalla M.L., Sant’Anna H.P., Saraiva M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopusEthnic background and CYP2D6 genetic polymorphisms in Costa Ricans
ArticleAbstract: CYP2D6 differences have already been demonstrated within Latin American populations by the CEIBA.FPPalabras claves:Afro-Caribbean, Amerindian, COSTA RICA, CYP2D6, MESTIZO, Poor metabolizers, populations, Ultrarapid metabolizersAutores:Adrián LLerena, Barrantes R., Calzadilla L.R., Céspedes-Garro C., Enrique Terán, Estévez-Carrizo F.E., Grazina M., Jiménez-Arce G., López-López M., María-Eugenia G.N., Moya G.E., Ortiz-López R., Ramírez-Roa R., Rodeiro I., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M.Fuentes:scopusOrigin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
ArticleAbstract: While South Americans are underrepresented in human genomic diversity studies, Brazil has been a claPalabras claves:Bambuí cohort study of ageing, Latin America, Pelotas birth cohort study, Population genetics, Salvador SCAALAAutores:Araujo G.S., Beleza S., Berg D.E., Cabrera L., Costa G.N.O., Debortoli G., Duarte D., Duarte N.E., Fiaccone R.L., Figueiredo C.A.V., Ghirotto S., Gilman R.H., Gonçalves V.F., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Machado M., Magalhães W.C.S., Marrero A.R., Mauricio L. Barreto, Moreira R.G., Muniz Y.C., Pereira A.C., Rodrigues L.C., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santos H.C., Scliar M.O., Silva T.M., Soares-Souza G.B., Tarazona-Santos E.M., Weissensteiner H., Yeager M., Zamudio R.Fuentes:scopusOrigins, admixture dynamics, and homogenization of the african gene pool in the americas
ArticleAbstract: The Transatlantic Slave Trade transportedmore than 9 million Africans to the Americas between the eaPalabras claves:Admixture dynamics, African Diaspora, MESTIZAJE, Transatlantic Slave TradeAutores:Alvim I.O., Aquino M.M., Araujo G.S., Araújo N.M., Bergen A.W., Borda V., Catira Bortolini M., Chanock S.J., Dean M., Furlan V., Gilman R.H., Gouveia M.H., Guio H., Horta B.L., Kehdy F.S.G., Leal T.P., Liboredo R., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Michelin L.A., Moreira R.G., Pereira A.C., Rocha J., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santolalla M.L., Scliar M.O., Soares-Souza G.B., Tarazona-Santos E.M., Tishkoff S.A., Yeager M., Zamudio R., Zolini C.Fuentes:scopusInterethnic variability of CYP2D6 alleles and of pbkp_redicted and measured metabolic phenotypes across world populations
ReviewAbstract: Introduction: The frequency of CYP2D6 alleles, related to either a lack of or increased enzymatic acPalabras claves:CYP2D6, CYP2D6∗10, CYP2D6∗17, CYP2D6∗29, CYP2D6∗4, CYP2D6∗41, ethnicity, Poor metabolizers, population pharmacogenetics, Ultrarapid metabolizersAutores:Adrián LLerena, Humberto Fariñas, Naranjo M.E.G., Penãs-Lledó E.M., Rodrigues-Soares F., Tarazona-Santos E.M.Fuentes:scopusLong noncoding RNA polymorphisms influence susceptibility to endemic pemphigus foliaceus
ArticleAbstract: Background: Pemphigus foliaceus (PF) is an epidermal autoimmune disease, characterized by the presenPalabras claves:Autores:Augusto D.G., de Almeida R.C., Horta B.L., Lima-Costa M.F., Lobo-Alves S.C., Magalhães W.C.S., Mauricio L. Barreto, Petzl-Erler M.L., Tarazona-Santos E.M.Fuentes:scopus