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scopus(6)
Delivery of rhBMP-2 plasmid DNA complexes via a PLLA/collagen electrospun scaffold induces ectopic bone formation
ArticleAbstract: The development of effective strategies for gene delivery is a critical goal in DNA-based tissue engPalabras claves:BMP-2, Bone formation, complexes, Electrospun, scaffoldAutores:David Edward Komatsu, Hadjiargyrou M., Zhao X.Fuentes:scopusActivation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair
ArticleAbstract: One of the immediate sequelae of bone fracture is regional hypoxia resulting from vasculature disrupPalabras claves:Angiogenesis, bone, Callus, Fracture, HIF-1α, HypoxiaAutores:David Edward Komatsu, Hadjiargyrou M.Fuentes:scopusEnhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1α deficiency
ArticleAbstract: HIF-1α activates genes under hypoxia and was hypothesized to regulate bone regeneration. SurprisinglPalabras claves:apoptosis, bone, Fracture, Hypoxia-inducible factor 1α, REGENERATIONAutores:Bosch-Marce M., David Edward Komatsu, Hadjiargyrou M., Semenza G.L.Fuentes:scopusIdentification of the microRNA transcriptome during the early phases of mammalian fracture repair
ArticleAbstract: Fracture repair is a complex process that involves multiple biological processes requiring spatiotemPalabras claves:bone, MiRNA, REGENERATION, regulation, Transcriptional, TranscriptomeAutores:David Edward Komatsu, Hadjiargyrou M., Zhi J.Fuentes:scopusMicroRNAs and fracture healing: Pre-clinical studies
ArticleAbstract: During the past several years, pre-clinical experiments have established that microRNAs (miRNAs), smPalabras claves:Chondrocytes, exosomes, Fracture healing, miRNAs, OsteoblastsAutores:David Edward Komatsu, Duque E., Hadjiargyrou M.Fuentes:scopusMolecular cloning and characterization of Mustang, a novel nuclear protein expressed during skeletal development and regeneration
ArticleAbstract: Bone regeneration occurs as a series of events that requires temporal and spatial orchestration of nPalabras claves:Fracture, Gene, Healing, novel, repairAutores:David Edward Komatsu, Hadjiargyrou M., Lombardo F.Fuentes:scopus